N-Methyltyramine

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N-Methyltyramine

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N-Methyltyramine
Identifiers
CAS number 370-98-9 YesY
PubChem 9727
ChemSpider 9345 YesY
ChEBI CHEBI:17458
Jmol-3D images Image 1
Properties
Molecular formula C9H13NO
Molar mass 151.21 g mol−1
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

N-Methyltyramine (NMT), also known as 4-hydroxy-N-methylphenethylamine, is a natural phenethylamine alkaloid found in a variety of plants. Biosynthetically, it is produced by the methylation of tyramine via the action of the enzyme tyramine N-methyltransferase.[1]

It is known to be a stimulator of pancreatic secretions.[2]

NMT has been shown to be an agonist of the TAAR1, similarly to its parent compound tyramine.[3]

See also

References

  1. ^ Tyrosine metabolism - Reference pathway, Kyoto Encyclopedia of Genes and Genomes (KEGG)
  2. ^ Tsutsumi, E; Kanai, S; Ohta, M; Suwa, Y; Miyasaka, K (2010). "Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats". Alcoholism, clinical and experimental research 34 Suppl 1: S14–7. doi:10.1111/j.1530-0277.2009.00893.x. PMID 19298333. 
  3. ^ Lindemann L, Hoener MC (May 2005). "A renaissance in trace amines inspired by a novel GPCR family". Trends in Pharmacological Sciences 26 (5): 274–81. doi:10.1016/j.tips.2005.03.007. PMID 15860375. http://linkinghub.elsevier.com/retrieve/pii/S0165-6147(05)00079-9. 



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