Nacolomab tafenatox
Wikipedia on Answers.com:
Top
Nacolomab tafenatox
| Monoclonal antibody | |
|---|---|
| Type | Fab fragment |
| Source | Mouse |
| Target | colorectal tumor antigen C242 |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 150631-27-9  |
| ATC code | None |
| Chemical data | |
| Formula | ? |
 (what is this?) (verify) |
|
Nacolomab tafenatox is a mouse monoclonal antibody[1] designed for the treatment of colorectal cancer.[citation needed] The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).[1]
VH, VL: variable (antigen binding) domains of antibody fragment
CH1, CL: constant domains of antibody fragment
SAg: enterotoxin A (acting as a superantigen)
See also
- Naptumomab estafenatox, a drug with a similar chemical structure and mechanism
References
 |
This monoclonal antibody-related article is a stub. You can help Wikipedia by expanding it. |
 |
This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it. |
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
Post a question - any question - to the WikiAnswers community:
Copyrights:
Wikipedia on Answers.com
This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article Nacolomab tafenatox.
Read more