Nebacumab

Nebacumab ^?

Monoclonal antibody
Type	Whole antibody
Source	Human
Target	endotoxin
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	138661-01-5 N
ATC code	J06BC01
KEGG	D05126 Y
Chemical data
Formula	?
N(what is this?)  (verify)

Nebacumab is a human monoclonal antibody developed for the treatment of sepsis.^[1] It has been withdrawn in 1993 because it failed to reduce mortality in clinical trials.^[2]

References

1. ^ Derkx, B.; Wittes, J.; McCloskey, R. (1999). "Randomized, Placebo‐Controlled Trial of HA‐1A, a Human Monoclonal Antibody to Endotoxin, in Children with Meningococcal Septic Shock". Clinical Infectious Diseases 28 (4): 770–726. doi:10.1086/515184. PMID 10825037.  edit
2. ^ WHO: Consolidated List of Products

v · d · eMonoclonal antibodies for infectious disease and toxins Fungal ("-fung-") Human ("-fungu-") Efungumab Viral ("-vi(r)-") Human ("-viru-") Exbivirumab • Foravirumab • Libivirumab • Rafivirumab • Regavirumab • Sevirumab • Tuvirumab Humanized ("-vizu-") Felvizumab • Motavizumab • Palivizumab • Suvizumab Bacterial ("-ba(c)-") Human ("-bacu-") Nebacumab • Panobacumab • Raxibacumab Mouse ("-baco-") Edobacomab Chimeric ("-baxi-") Pagibaximab Humanized ("-bazu-") Tefibazumab† Toxin ("-tox(a)-") Humanized ("-toxazu-") Urtoxazumab #WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

v · d · eImmune sera and immunoglobulins (J06) Polyclonal antibodies IVIG Rho(D) immune globulin · Hepatitis B immune globulin · Zoster-immune globulin Antiserum Antivenom Monoclonal antibodies Palivizumab · Nebacumab M: BAC bact (clas) gr+f/gr+a(t)/gr-p(c)/gr-o drug(J1p, w, n, m, vacc)

This antiinfective drug article is a stub. You can help Wikipedia by expanding it.v · d · e

This monoclonal antibody-related article is a stub. You can help Wikipedia by expanding it.v · d · e

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)