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Portal ceroid-laden macrophages mean necrosis of hepatocytes at the interface of portal tracts. The necrosis may be induced by the inflammation including interface hepatitis. Macrophages phagocyte the necrotic hepatocytes, then they have abundant brownish cytoplasm, which is called ceroid-laden feature.

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Portal ceroid-laden macrophages mean necrosis of hepatocytes at the interface of portal tracts. The necrosis may be induced by the inflammation including interface hepatitis. Macrophages phagocyte the necrotic hepatocytes, then they have abundant brownish cytoplasm, which is called ceroid-laden feature.

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