Niacin/lovastatin

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Niacin/lovastatin


Combination of
Niacin	Vitamin
Lovastatin	Statin
Clinical data
Pregnancy cat.	X(US)
Legal status	℞-only (US)
Routes	Oral
Identifiers
ATC code	C10BA01
Y(what is this?) (verify)

Niacin/lovastatin (trade names Advicor, Mevacor) is a drug combination used for the treatment of dyslipidemia. It is a combination of the vitamin niacin and the statin drug lovastatin. The combination preparation is marketed by Abbott Laboratories

It was approved by the FDA on December 17, 2001.

Dosage

The combination is available as tablets containing:.^[1]

500 mg/20 mg
750 mg/20 mg
1000 mg/20 mg
1000 mg/40 mg

References

^ "Advicor package insert, How Supplied section". http://www.rxlist.com/cgi/generic/advicor_ids.htm. Retrieved 2008-03-15.

External links

Advicor website

Lipid modifying agents (C10)

GI tract

Cholesterol absorption inhibitors, NPC1L1	Ezetimibe • SCH-48461

Bile acid sequestrants/resins (LDL)	Cholestyramine • Colestipol • Colestilan • Colextran • Colesevelam

Liver

Statins (HMG-CoA reductase, LDL)	Simvastatin^# • Atorvastatin • Fluvastatin • Lovastatin • Mevastatin • Pitavastatin • Pravastatin • Rosuvastatin • Cerivastatin^‡

Niacin and derivatives (HDL and LDL)	Niceritrol • Niacin • Nicofuranose • Aluminium nicotinate • Nicotinyl alcohol • Acipimox

Blood vessels

Fibrates (PPAR)	Clofibrate^‡ • Bezafibrate • Aluminium clofibrate • Gemfibrozil • Fenofibrate • Simfibrate • Ronifibrate • Ciprofibrate • Etofibrate • Clofibride • Clinofibrate

CETP inhibitors (HDL)	Anacetrapib^† • Dalcetrapib • Evacetrapib • Torcetrapib^§

Combinations

Niacin/lovastatin • Niacin/simvastatin • Ezetimibe/simvastatin • Niacin/laropiprant

Other

Dextrothyroxine • Probucol • Tiadenol • Benfluorex • Meglutol • Omega-3-triglycerides • Magnesium pyridoxal 5-phosphate glutamate • Policosanol • Lapaquistat^§ • Mipomersen • Alipogene tiparvovec

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

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