Results for nilutamide
On this page:
 
Drug Info:

Nilutamide

Brand names: Nilandron™



Nilutamide tablets

What are nilutamide tablets?

NILUTAMIDE (Nilandron(TM)) blocks the effect of the male hormone called testosterone. Prostate cancer responds to the removal of androgens. Nilutamide is used in combination with surgical treatment. Generic nilutamide tablets are not yet available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• alcoholism
• anemia
• liver disease
• lung disease
• visual problems
• an unusual or allergic reaction to nilutamide, other medicines, foods, dyes, or preservatives
• trying to conceive with your partner

How should I take this medicine?

Take nilutamide tablets by mouth at the same time each day. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Do not take your medicine more often than directed. Finish the full course prescribed by your doctor or health care professional, even if the tablets make you feel unwell. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you vomit after taking a dose, call your prescriber or health care professional for advice.

What drug(s) may interact with nilutamide?

• ethanol
• phenytoin
• theophylline
• warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking nilutamide?

Visit your prescriber or health care professional for regular checks on your progress. At first your condition can get worse, but it will then improve as you continue your treatment. Improvement in your condition can take several days.

Nilutamide may affect your vision. If you notice a change in how your eyes adjust to the dark after starting nilutamide, do not drive at night or through tunnels. This side effect usually goes away. Wearing tinted glasses may help.

You should avoid alcohol while taking nilutamide. Mixing alcohol and nilutamide can cause more side effects.

What side effects may I notice from taking nilutamide?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• difficulty breathing when exerting yourself
• chest pain
• fever
• persistent cough
• skin rash, hives, or itching
• swelling of the lips, tongue or face
• vomiting
• yellowing of the skin

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• constipation
• diarrhea
• dizziness
• hot flashes
• nausea
• vision disturbance (trouble adjusting to the dark)

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.


Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

 
 
Wikipedia: nilutamide
Nilutamide.svg
Nilutamide
Systematic (IUPAC) name
5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]
imidazolidine-2,4-dione
Identifiers
CAS number 63612-50-0
ATC code L02BB02
PubChem 4493
DrugBank APRD00150
Chemical data
Formula C12H10F3N3O4 
Mol. mass 317.221 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 38.0 to 59.1 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Nilutamide is an antiandrogen medication used in the treatment of advanced stage prostate cancer. Nilutamide blocks the androgen receptor, preventing its interaction with testosterone. Because most prostate cancer cells rely on the stimulation of the androgen receptor for growth and survival, nilutamide can prolong life in men with prostate cancer. Nilutamide is marketed under the name Nilandron in the United States.

References

  • Kassouf W, Tanguay S, Aprikian AG. Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails. J. Urol. 2003 May;169(5):1742-4. PMID 12686822



 
 

Join the WikiAnswers Q&A community. Post a question or answer questions about "nilutamide" at WikiAnswers.

 

Copyrights:

Drug Info. Gold Standard. Copyright © 2008 by Gold Standard. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nilutamide" Read more

Search for answers directly from your browser with the FREE Answers.com Toolbar!  
Click here to download now. 

Get Answers your way! Check out all our free tools and products.

On this page:   E-mail   print Print  Link  

 

Keep Reading

Mentioned In: