Nobel prizes in chemistry| Year | Name of prizewinner(s) | Nature of work or discovery |
| 1901 | Jacobus Henricus Van't Hoff (1852–1911) Dutch | Discovery of the laws of chemical dynamics and osmotic pressure in solutions |
| 1902 | Hermann Emil Fischer (1852–1919) German | Work on sugar and purine syntheses |
| 1903 | Svante August Arrhenius (1859–1927) Swedish | The electrolytic theory of dissociation |
| 1904 | Sir William Ramsay (1852–1916) British | Discovery of the inert gaseous elements in air and the determination of their place in the periodic system |
| 1905 | Johann Friedrich Wilhelm Adolf Von Baeyer (1835–1917) German | Advancement of organic chemistry and the chemical industry through work on organic dyes and hydroaromatic compounds |
| 1906 | Henri Moissan (1852–1907) French | Investigation and isolation of the element fluorine, and for his electric furnace |
| 1907 | Eduard Buchner (1860–1917) German | Biochemical researches and the discovery of cell-free fermentation |
| 1908 | Lord Ernest Rutherford (1871–1937) New Zealand–British | Investigations into the disintegration of the elements and the chemistry of radioactive substances |
| 1909 | Wilhelm Ostwald (1853–1932) Latvian–German | Work on catalysis and investigations into the fundamental principles governing chemical equilibria and rates of reaction |
| 1910 | Otto Wallach (1847–1931) German | Pioneering work in the field of alicyclic compounds |
| 1911 | Marie Curie (1867–1934) Polish–born French | Discovery of the elements radium and polonium, the isolation of radium, and the study of this element |
| 1912 | Victor Grignard (1871–1935) French | Discovery of the Grignard reagent |
| Paul Sabatier (1854–1941) French | Method of hydrogenating organic compounds in the presence of finely divided metals |
| 1913 | Alfred Werner (1866–1919) German-born Swiss | Work on the linkage of atoms in molecules, especially in inorganic chemistry |
| 1914 | Theodore William Richards (1868–1928) US | Accurate determinations of the atomic weights of many chemical elements |
| 1915 | Richard Martin Willstätter (1872–1942) German | Work on plant pigments, especially chlorophyll |
| 1918 | Fritz Haber (1868–1934) German | The synthesis of ammonia from its elements |
| 1920 | Walther Hermann Nernst (1864–1941) German | Work in thermochemistry |
| 1921 | Frederick Soddy (1877–1956) British | Work on the chemistry of radioactive substances and investigations into the origin and nature of isotopes |
| 1922 | Francis William Aston (1877–1945) British | Discovery, by means of his mass spectrograph, of isotopes in a large number of nonradioactive elements |
| 1923 | Fritz Pregl (1869–1930) Austrian | Invention of the method of microanalysis of organic substances |
| 1925 | Richard Adolf Zsigmondy (1865–1929) Austrian–German | Demonstration of the heterogenous nature of colloid solutions and for the methods developed to study them |
| 1926 | Theodor Svedberg (1884–1971) Swedish | Work on disperse systems |
| 1927 | Heinrich Otto Wieland (1877–1957) German | Investigations of the constitution of the bile acids and related substances |
| 1928 | Adolf Otto Reinhold Windaus (1876–1959) German | Work on the constitution of the sterols and their connection with the vitamins |
| 1929 | Sir Arthur Harden (1865–1940) British | Investigations on the fermentation of sugar and fermentative enzymes |
| Hans Karl August Simon Von Euler-Chelpin (1873–1964) German–Swedish | |
| 1930 | Hans Fischer (1881–1945) German | Work on the constitution of haemin and chlorophyll, especially the synthesis of haemin |
| 1931 | Carl Bosch (1874–1940) German Friedrich Bergius (1884–1949) German | Contributions to the invention and development of chemical high pressure methods |
| 1932 | Irving Langmuir (1881–1957) US | Discoveries and investigations in surface chemistry |
| 1934 | Harold Clayton Urey (1893–1981) US | Discovery of heavy hydrogen (deuterium) |
| 1935 | Frédéric Joliot (1900–1958) French Irène Joliot-Curie (1897–1956) French | Synthesis of new radioactive elements |
| 1936 | Petrus (Peter) Josephus Wilhelmus Debye (1884–1966) Dutch | Contributions to our knowledge of molecular structure through investigations on dipole moments and on the diffraction of X-rays and electrons in gases |
| 1937 | Sir Walter Norman Haworth (1883–1950) British | Investigation of carbohydrates and vitamin C |
| Paul Karrer (1889–1971) Russian–Swiss | Investigations on carotenoids, flavins, and vitamins A and B2 |
| 1938 | Richard Kuhn (1900–1967) Austrian-born German | Work on carotenoids and vitamins (declined the award because of political pressure but later received the diploma and the medal) |
| 1939 | Adolf Friedrich Johann Butenandt (1903–1995) German | Work on sex hormones |
| 1939 | Leopold (Lavoslav) Stephen Ruzicka (1887–1976) Croatian–Swiss | Work on polymethylenes and higher terpenes |
| 1943 | George De Hevesy (1885–1966) Hungarian-born Swedish | Work on the use of isotopes as tracers in the study of chemical processes |
| 1944 | Otto Hahn (1879–1968) German | Discovery of the fission of heavy nuclei |
| 1945 | Artturi Ilmari Virtanen (1895–1973) Finnish | Research and inventions in agricultural and nutrition chemistry, especially for a fodder-preservation method |
| 1946 | James Batcheller Sumner (1887–1955) US | Discovery that enzymes can be crystallized |
| John Howard Northrop (1891–1987) US | Preparation of enzymes and virus proteins in a pure form |
| Wendell Meredith Stanley US (1904–1971) | |
| 1947 | Sir Robert Robinson (1886–1975) British | Investigations on plant products of biological importance, especially the alkaloids |
| 1948 | Arne Wilhelm Kaurin Tiselius (1902–1971) Swedish | Work on electrophoresis and adsorption analysis, especially discoveries concerning the complex nature of the serum proteins |
| 1949 | William Francis Giauque (1895–1982) US | Contributions to the field of chemical thermodynamics, particularly the behaviour of substances at very low temperatures |
| 1950 | Otto Paul Hermann Diels (1876–1954) German | Discovery and development of the diene synthesis (the Diels–Alder reaction) |
| Kurt Alder (1902–1958) German | |
| 1951 | Edwin Mattison McMillan (1907–1991) US | Work on the chemistry of the transuranium elements |
| Glenn Theodore Seaborg (1912–1999) US | |
| 1952 | Archer John Porter Martin (1910–2002) British | Invention of the technique of partition chromatography |
| Richard Laurence Millington Synge (1914–1994) British | |
| 1953 | Hermann Staudinger (1881–1965) German | Discoveries in the field of macromolecular chemistry |
| 1954 | Linus Carl Pauling (1901–1978) US | Work on the nature of the chemical bond and its application to the elucidation of the structure of complex substances |
| 1955 | Vincent Du Vigneaud (1901–1978) US | Work on biochemically important sulphur compounds, especially for the first synthesis of a polypeptide hormone |
| 1956 | Sir Cyril Norman Hinshelwood (1897–1967) British | Studies of the mechanism of chemical reactions |
| Nikolay Nikolaevich Semenov (1896–1986) Soviet | |
| 1957 | Lord Alexander R. Todd (1907–1997) British | Work on nucleotides and nucleotide coenzymes |
| 1958 | Frederick Sanger (1918– ) British | Work on the structure of proteins, especially insulin |
| 1959 | Jaroslav Heyrovsky (1890–1967) Czech | Discovery and development of polarography |
| 1960 | Willard Frank Libby (1908–1980) US | Discovery and development of the technique of carbon–14 dating |
| 1961 | Melvin Calvin (1911– ) US | Work on carbon dioxide assimilation in plants |
| 1962 | Max Ferdinand Perutz (1914–2002) Austrian–British | Studies of the structures of globular proteins |
| Sir John Cowdery Kendrew (1917–1997) British | |
| 1963 | Karl Ziegler (1898–1973) German | Discoveries concerning the chemistry and technology of high polymers |
| Giulio Natta (1903–1979) Italian | |
| 1964 | Dorothy Crowfoot Hodgkin (1910–1994) British | Determinations by X-ray techniques of the structures of important biochemical substances |
| 1965 | Robert Burns Woodward (1917–1979) US | Achievements in the art of organic synthesis |
| 1966 | Robert S. Mulliken (1896–1986) US | Work concerning chemical bonds and the electronic structure of molecules using molecular orbital theory |
| 1967 | Manfred Eigen (1927– ) German | Studies of extremely fast chemical reactions, effected by disturbing the equlibrium by means of very short pulses of energy |
| Ronald George Wreyford Norrish (1897–1978) British | |
| Lord George Porter (1920–2002) British | |
| 1968 | Lars Onsager (1903–1976) Norwegian–US | Discovery of the reciprocal relations used in the thermodynamics of irreversible processes |
| 1969 | Sir Derek H. R. Barton (1918–1998) British | Development of the concept of conformation and its application in chemistry |
| Odd Hassel (1897–1981) Norwegian | |
| 1970 | Luis F. Leloir (1906–1987) Argentinian | Discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates |
| 1971 | Gerhard Herzberg (1904–1999) German–Canadian | Work on the electronic structure and geometry of molecules and free radicals |
| 1972 | Christian B. Anfinsen (1916–1995) US | Work on ribonuclease, especially the connection between the amino acid sequence and the active conformation |
| Stanford Moore (1913–1982) US | Contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule |
| William H. Stein (1911–1980) US | |
| 1973 | Ernst Otto Fischer (1918–2007) German | Pioneering work, performed independently, on the chemistry of the sandwich compounds |
| Sir Geoffrey Wilkinson (1921–1996) British | |
| 1974 | Paul J. Flory (1910–1985) US | Theoretical and experimental work on the physical chemistry of macromolecules |
| 1975 | Sir John Warcup Cornforth (1917– ) Australian–British | Work on the stereochemistry of enzyme-catalysed reactions |
| 1975 | Vladimir Prelog (1906–1998) Bosnian–Swiss | Work on the stereochemistry of organic molecules and reactions |
| 1976 | William N. Lipscomb (1919– ) US | Studies on the structure of boranes, illuminating problems of chemical bonding |
| 1977 | Ilya Prigogine (1917–2003) Russian–Belgian | Contributions to non-equilibrium thermodynamics, particularly the theory of dissipative structures |
| 1978 | Peter D. Mitchell (1920–1992) British | Formulation of the chemiosmotic theory |
| 1979 | Herbert C. Brown (1912–2004) British–US | Development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis |
| Georg Wittig (1897–1987) German | |
| 1980 | Paul Berg (1926– ) US | Fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant DNA |
| Walter Gilbert (1932– ) US | Contributions concerning the determination of base sequences in nucleic acids |
| Frederick Sanger (1918– ) British | |
| 1981 | Kenichi Fukui (1918–1998) Japanese | Theories, developed independently, concerning the course of chemical reactions (frontier-orbital theory and the Woodward–Hoffmann rules) |
| Roald Hoffmann (1937– ) Polish–US | |
| 1982 | Sir Aaron Klug (1926– ) Lithuanian–British | Development of crystallographic electron microscopy and the structural elucidation of biologically important nucleic acid–protein complexes |
| 1983 | Henry Taube (1915–2005) Canadian–US | Work on the mechanisms of electron-transfer reactions, especially in metal complexes |
| 1984 | Robert Bruce Merrifield (1921–2006) US | Development of methodology for chemical synthesis on a solid matrix |
| 1985 | Herbert A. Hauptman (1917– ) US | Development of direct methods for the determination of crystal structures |
| Jerome Karle (1918– ) US | |
| 1986 | Dudley R. Herschbach (1932– ) US | Research on the dynamics of chemical elementary processes |
| Yuan T. Lee (1936– ) Taiwanese | |
| John C. Polanyi (1929– ) Canadian | |
| 1987 | Donald J. Cram (1919–2001) US | Development and use of molecules with structure-specific interactions of high selectivity (crown ethers and cryptands) |
| Jean–Marie Lehn (1939– ) French | |
| Charles J. Pedersen (1904–1989) Norwegian | |
| 1988 | Johann Deisenhofer (1943– ) German | Determination of the three-dimensional structure of a photosynthetic reaction centre |
| Robert Huber (1937– ) German | |
| Hartmut Michel (1948– ) German | |
| 1989 | Sidney Altman (1939– ) Canadian–US | Discovery of the catalytic properties of RNA |
| Thomas R. Cech (1947– ) US | |
| 1990 | Elias James Corey (1928– ) US | Development of the theory and methodology of organic synthesis (retrosynthetic analysis) |
| 1991 | Richard R. Ernst (1933– ) Swiss | Development of high resolution nuclear magnetic resonance (NMR) spectroscopy |
| 1992 | Rudolph A. Marcus (1923– ) Canadian–US | Work on electron–transfer reactions in chemical systems |
| 1993 | Kary B. Mullis (1944– ) US | Discovery of the polymerase chain reaction |
| Michael Smith (1932–2000) British–Canadian | Work on oligonucleotide-based site-directed mutagenesis and its use for protein studies |
| 1994 | George A. Olah (1927– ) Hungarian–US | Work on carbocation chemistry |
| 1995 | Paul Crutzen (1933– ) Dutch | Work in atmospheric chemistry, particularly the formation and decomposition of ozone |
| Mario J. Molina (1943– ) Mexican–US | |
| F. Sherwood Rowland (1927– ) US | |
| 1996 | Robert F. Curl (1933– ) US | Discovery of fullerenes |
| Sir Harold W. Kroto (1939– ) British | |
| Richard Smalley (1943–2005) US | |
| 1997 | Paul D. Boyer (1918– ) US | Elucidation of the mechanism underlying the synthesis of ATP |
| John E. Walker (1941– ) British | |
| Jens C. Skou (1918– ) Danish | Discovery of an ion-transporting enzyme, Na+,K+-ATPase |
| 1998 | Walter Kohn (1923– ) Austrian–US | Development of density-functional theory |
| John A. Pople (1925–2004) British | Development of computational methods in quantum chemistry |
| 1999 | Ahmed H. Zewail (1946– ) Egyptian | Studies of the transition states of chemical reactions using femtosecond spectroscopy |
| 2000 | Alan J. Heeger (1936– ) US | Discovery and development of conductive polymers |
| Alan G. MacDiarmid (1927–2007) New Zealand–US | |
| Hideki Shirakawa (1936– ) Japanese | |
| 2001 | William S. Knowles (1917– ) US | Work on chirally catalysed hydrogenation reactions |
| Ryoji Noyori (1938– ) Japanese | |
| K. Barry Sharpless (1941– ) US | Work on chirally catalysed oxidation reactions |
| 2002 | John B. Fenn (1917– ) US | Development of ionization methods for mass spectrometric analyses of biological macromolecules |
| Koichi Tanaka (1959– ) Japanese | |
| Kurt Wuthrich (1938– ) Swiss | Development of NMR spectroscopy for determining the structure of biological macromolecules in solution |
| 2003 | Peter Agre (1949– ) US | Discovery of water channels in cell membranes |
| Roderick MacKinnon (1956– ) US | Structural and mechanistic studies of ion channels in cell membranes |
| 2004 | Aaron Ciechanover (1947– ) Israeli | Discovery of ubiquitin-mediated protein degradation |
| Avram Hershko (1937– ) | |
| Hungarian–Israeli Irwin Rose (1926– ) US | |
| 2005 | Yves Chauvin (1930– ) French | Development of the metathesis method in organic synthesis |
| Robert H. Grubbs (1942– ) US | |
| Richard R. Schrock (1945– ) US | |
| 2006 | Roger D. Kornberg (1947– ) US | Studies of the molecular basis of eukaryotic transcription |
| 2007 | Gerhard Erti (1936– ) German | Studies of chemical processes on solid surfaces |