noncompetitive inhibition

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(¦nän·kəm′ped·əd·iv ′in·ə′bish·ən)

(biochemistry) Enzyme inhibition in which the inhibitor can combine with either the free enzyme or the enzyme-substrate complex so that the inhibitor does not compete with the substrate for the enzyme.


American Heritage Stedman's Medical Dictionary:

non·com·pet·i·tive inhibition

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(nŏn'kəm-pĕt'ĭ-tĭv)
n.

Enzyme inhibition in which the inhibiting compound does not compete with the natural substrate for the active site on the enzyme but inhibits reaction by combining with the enzyme-substrate complex after the complex is formed.

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