| Brain: Nucleus ambiguus | ||
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| Transverse section of medulla oblongata below the middle of the olive. ("Nucleus ambiguus" labeled at center right.) | ||
| Gray's | subject #187 779 | |
| NeuroNames | hier-762 | |
| NeuroLex ID | birnlex_2650 | |
The nucleus ambiguus (literally "ambiguous nucleus") is a region of histologically disparate cells located just dorsal (posterior) to the inferior olivary nucleus in the lateral portion of the upper (rostral) medulla. It receives upper motor neuron innervation directly via the corticobulbar tract.
This nucleus gives rise to the somatic efferent motor fibers of the vagus nerve (CN X) terminating in the laryngeal and pharyngeal muscles, as well as to the efferent motor fibers of the glossopharyngeal nerve (CN IX) terminating in the stylopharyngeus.
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Areas supplied
The muscles supplied by the vagus (included with this is the cranial part of the accessory nerve), such as levator veli palatini, are also necessary to swallow properly through integration by the nucleus of the solitary tract. The vagus also supplies the upper part of the esophagus, and other parts of the pharynx and larynx.
As well as motor neurons, the nucleus ambiguus contains preganglionic parasympathetic neurons for the heart[1]. These neurons are cardioinhibitory [2] This cardioinhibitory effect is the means by which quick changes in blood pressure are achieved. That is, through integrated and antagonistic system with sympathetic outflow from the vasomotor center of the brainstem, the parasympathetic outflow arising from the nucleus ambiguus and dorsal motor nucleus of the vagus nerve acts to decrease cardiac activity in response to fast increases in blood pressure.
Additional images
 Section of the medulla oblongata at about the middle of the olive. |
 The cranial nerve nuclei schematically represented; dorsal view. Motor nuclei in red; sensory in blue. |
 Nuclei of origin of cranial motor nerves schematically represented; lateral view. |
 The formatio reticularis of the medulla oblongata, shown by a transverse section passing through the middle of the olive. |
References
- ^ Role of the nucleus ambiguus in the regulation of heart rate and arterial pressure. BH Machado and MJ Brody. http://hyper.ahajournals.org/cgi/content/abstract/11/6/602
- ^ Localization of vagal cardioinhibitory preganglionic neurons with rat brain stem. Nosaka S et al. http://www3.interscience.wiley.com/journal/109685993/abstract
External links
- Medical Neurosciences discuss the nucleus ambiguus.
- -1664090053 at GPnotebook
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