O-1057
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O-1057
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|---|---|
| Systematic (IUPAC) name | |
| 3-(5'-cyano-1',1'-dimethylpentyl)-1-(4-N-morpholinobutyryloxy)-Δ8-tetrahydrocannabinol | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| ATC code | ? |
| Chemical data | |
| Formula | C32H46N2O4 |
| Mol. mass | 522.717 g/mol |
| SMILES | eMolecules & PubChem |
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O-1057 is an analgesic cannabinoid derivative created by Organix Inc. for use in scientific research. Unlike most cannabinoids discovered to date, it is water soluble, which gives it considerable advantages over many related cannabinoids. It has moderate affinity for both CB1 and CB2 receptors, with Ki values of 8.36nM at CB1 and 7.95nM at CB2.[1]
See also
References
- ^ Pertwee RG, Gibson TM, Stevenson LA, Ross RA, Banner WK, Saha B, Razdan RK, Martin BR. O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties. British Journal of Pharmacology. 2000 Apr;129(8):1577-84. PMID 10780961
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