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Class A:
Rhodopsin like |
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Adenosine ( A1, A2A, A2B, A3) · P2Y ( 1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)
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Other
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Acetylcholine ( M1, M2, M3, M4, M5) · Dopamine ( D1, D2, D3, D4, D5) · Histamine ( H1, H2, H3, H4) · Melatonin ( 1A, 1B, 1C) · TAAR ( 1, 2, 3, 5, 6, 8, 9)
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Metabolites and
signaling molecules
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Other
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Bile acid · Cannabinoid ( CB1, CB2, GPR ( 18, 55, 119)) · EBI2 · Estrogen · Free fatty acid ( 1, 2, 3, 4) · Lactate · Lysophosphatidic acid ( 1, 2, 3, 4, 5, 6) · Lysophospholipid ( 1, 2, 3, 4, 5, 6, 7, 8) · Niacin ( 1, 2) · Oxoglutarate · PAF · Sphingosine-1-phosphate ( 1, 2, 3, 4, 5) · Succinate
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Peptide
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Other
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Anaphylatoxin ( C3a, C5a) · Angiotensin ( 1, 2) · Apelin · Bombesin ( BRS3, GRPR, NMBR) · Bradykinin ( B1, B2) · Chemokine · Cholecystokinin ( A, B) · Endothelin ( A, B) · Formyl peptide ( 1, 2, 3) · FSH · Galanin ( 1, 2, 3) · GHB receptor · Gonadotropin-releasing hormone ( 1, 2) · Ghrelin · Kisspeptin · Luteinizing hormone/choriogonadotropin · MAS ( 1, 1L, D, E, F, G, X1, X2, X3, X4) · Melanocortin ( 1, 2, 3, 4, 5) · MCHR ( 1, 2) · Motilin · Opioid ( Delta, Kappa, Mu, Nociceptin & Zeta, but not Sigma) · Orexin ( 1, 2) · Oxytocin · Prokineticin ( 1, 2) · Prolactin-releasing peptide · Relaxin ( 1, 2, 3, 4) · Somatostatin ( 1, 2, 3, 4, 5) · Tachykinin ( 1, 2, 3) · Thyrotropin · Thyrotropin-releasing hormone · Urotensin-II · Vasopressin ( 1A, 1B, 2)
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Miscellaneous
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GPR ( 1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 81, 82, 83, 84, 85, 87, 88, 92, 101, 103, 109A, 109B, 119, 120, 132, 135, 137B, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 173, 174, 176, 177, 182, 183)
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Other
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Adrenomedullin · Olfactory · Opsin ( 3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) · Protease-activated ( 1, 2, 3, 4) · SREB ( 1, 2, 3)
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| Class B: Secretin like |
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GPR ( 56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 155, 157)
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Other
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Brain-specific angiogenesis inhibitor ( 1, 2, 3) · Cadherin ( 1, 2, 3) · Calcitonin · CALCRL · CD97 · Corticotropin-releasing hormone ( 1, 2) · EMR ( 1, 2, 3) · Glucagon ( GR, GIPR, GLP1R, GLP2R) · Growth hormone releasing hormone · PACAPR1 · GPR · Latrophilin ( 1, 2, 3, ELTD1) · Methuselah-like proteins · Parathyroid hormone ( 1, 2) · Secretin · Vasoactive intestinal peptide ( 1, 2)
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Class C: Metabotropic
glutamate / pheromone |
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TAS1R ( 1, 2, 3) · TAS2R ( 1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 19, 20, 30, 31, 38, 39, 40, 41, 42, 43, 45, 46, 50)
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Other
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Calcium-sensing receptor · GABA B ( 1, 2) · Glutamate receptor ( Metabotropic glutamate ( 1, 2, 3, 4, 5, 6, 7, 8)) · GPRC6A · GPR ( 156, 158, 179) · RAIG ( 1, 2, 3, 4)
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Class F:
Frizzled / Smoothened |
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B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
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