osteodystrophy

(medicine) Any defective bone formation, as in rickets or dwarfism.

Defective formation of bone. Also called osteodystrophia.

Diseases of bone in which there is failure of normal development or abnormal metabolism in bone which is already mature. Principal clinical signs are distortion and enlargement of bones, susceptibility to fracture, and abnormalities of gait and posture. See also osteodystrophia fibrosa.

• hypertrophic o. — a disease of unknown etiology that occurs in young, rapidly growing dogs primarily of the large or giant breeds, in which there is pain and soft tissue swelling usually around the distal radius, ulna and tibia, lameness, and varying degrees of fever, lethargy and anorexia. Periosteal new bone is formed around the metaphyses and sometimes diaphyses, contributing to the enlargement of the limbs. The cause is unknown but hypovitaminosis C has at various times been suggested. Called also Möller–Barlow's disease (from a similar human disease), Barlow's disease, skeletal scurvy, infantile scurvy, osteodystrophy II, metaphyseal osteopathy, canine hypertrophic osteodystrophy.
• renal o. — see renal secondary hyperparathyroidism.

  Hypertrophic osteodystrophy in a 4-month-old Great Dane. By permission from Lamb CR, Diagnostic Imaging of the Dog and Cat, Mosby, 1993

The noun has one meaning:

Meaning #1: defective bone development; usually attributable to renal disease or to disturbances in calcium and phosphorus metabolism