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Many drugs can cause ototoxicity.
Antibiotics- amikacin (Amikin)
- streptomycin
- neomycin
- gentamicin (Garamycin)
- erythromycin (E-Mycin, Eryc)
- kanamycin (Kantrex
- tobramycin (Nebcin)
- netilmycin (Netromycin)
- vancomycin (Vancocin)
- cisplatin (Platinol AQ
- bleomycin (Blenoxane)
- vincristine (Oncovin)
- acetazolamide (Diamox)
- furosemide (Lasix)
- bumetanide (Bumex)
- ethacrynic acid (Edecrine)
A number of other drugs and chemicals may also cause ototoxicity. Aspirin overdose causes ringing in the ears. The antimalarial drugs quinine and chloroquine may also cause ear damage. Among the environmental chemicals that can cause ear damage are tin, lead, mercury, carbon monoxide, and carbon disulfide. This list is not complete, and many other drugs and chemicals, such as industrial solvents, may cause ear problems.
— Sam Uretsky, PharmD
