A mathematical function analogous to the calculation of pH. It is the negative log (p) of the constant of acid dissociation (Ka). When the pKa of a buffering agent equals the pH of the solution to be buffered, the buffering system is most effective. According to the Henderson Hasselbach equation, pKa = pH + log ([HOAc]/[OAc-]).
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 | Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more |
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