Pancreatic stellate cell
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Pancreatic stellate cell
Pancreatic stellate cells (PaSCs or PSCs) are myofibroblast-like cells that can switch between the quiescent and activated phenotypes, like hepatic stellate cells.[2] PaSCs reside in exocrine areas of the pancreas. When activated, PaSCs undergo activation, migrate to the injured location, and participate in tissue repair activities, secreting ECM components. PaSCs may play a role in the pathogenesis of pancreatitis and pancreatic cancer.[1]
See also
References
- ^ a b Jaster R (October 2004). "Molecular regulation of pancreatic stellate cell function". Mol. Cancer 3 (1): 26. doi:10.1186/1476-4598-3-26. PMC 524499. PMID 15469605. http://www.molecular-cancer.com/content/3//26.
- ^ Omary MB, Lugea A, Lowe AW, Pandol SJ (January 2007). "The pancreatic stellate cell: a star on the rise in pancreatic diseases". J. Clin. Invest. 117 (1): 50–9. doi:10.1172/JCI30082. PMC 1716214. PMID 17200706. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1716214.
External links
Media related to pancreatic stellate cell at Wikimedia Commons
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