paracrine

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Applied to cellular secretions that act on cells a short-distance from their site of secretion. For example, insulin-like growth factors secreted by a muscle cell may promote the growth of neighbouring muscle cells and connective tissues.

(păr'ə-krĭn)
adj.

Relating to the release of locally acting substances from endocrine cells.

Indicative of the action of the secretion of one kind of endocrine cell on another kind which is not the normal effector cell.

  • p. hormones — in contrast to true endocrines these hormones are not released into the bloodstream but into the surrounding tissues and act in the immediate vicinity, e.g. intestinal mucosal hormones.

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