parathyrin
Oxford Dictionary of Biochemistry:
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parathyrin
or parathyroid hormone
(abbr.: PTH); a 9.5 kDa polypeptide hormone of 83 amino-acid residues (bovine). It is derived from a 12.5 kDa precursor. Parathyrin acts in conjunction with calcitonin and other hormones to control calcium and phosphate metabolism; it elevates the blood calcium level by dissolving the salts in bone and preventing their renal excretion. Its effects are mediated by a G-protein-associated membrane receptor. Several mutations in the receptor cause a rare form of short-limbed dwarfism (or metaphyseal chondrodys-plasia). Mutations that lead to absence or dysfunction of the GSα subunit cause pseudohypoparathyroidism type 1a, in which there is also resistance to a wide variety of other hormones whose effects are mediated by this subunit. Proprietary name: Parathormone.
(abbr.: PTH); a 9.5 kDa polypeptide hormone of 83 amino-acid residues (bovine). It is derived from a 12.5 kDa precursor. Parathyrin acts in conjunction with calcitonin and other hormones to control calcium and phosphate metabolism; it elevates the blood calcium level by dissolving the salts in bone and preventing their renal excretion. Its effects are mediated by a G-protein-associated membrane receptor. Several mutations in the receptor cause a rare form of short-limbed dwarfism (or metaphyseal chondrodys-plasia). Mutations that lead to absence or dysfunction of the GSα subunit cause pseudohypoparathyroidism type 1a, in which there is also resistance to a wide variety of other hormones whose effects are mediated by this subunit. Proprietary name: Parathormone.
| parathion, paratartaric acid, parastatin | |
| parathyroid, parathyroid gland, parathyroid hormone |
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Oxford Dictionary of Biochemistry
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