pathway database

a database that links gene products and compounds in the cells of an organism to components on particular pathways. Such databases are used to facilitate gene function assignment and metabolic reconstruction. Examples include: BIND, which stores information on biomolecular interactions, molecular complexes, and pathways; EcoCyc, which houses metabolic, regulation, and signal transduction data on Escherichia coli; KEGG (Kyoto Encyclopedia of Genes and Genomes), which links human genes with networks of interacting molecules in the cell; WIT (what is there?), which houses metabolic, gene function, and phylogenetic data from multiple genomes; and HPRD (human protein reference database), an integrated pathway database of human reference proteins that contains domain architectures, PTMs, interaction networks, and disease associations for the human proteome.

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