Penamecillin

Penamecillin

Systematic (IUPAC) name
(acetyloxy)methyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	983-85-7
ATC code	J01CE06
PubChem	CID 13795
UNII	H0P1YE5581 Y
KEGG	D05406 Y
Chemical data
Formula	C19H22N2O6S
Mol. mass	406.45278
Y (what is this?)  (verify)

Penamecillin, a acetoxymethyl ester of benzylpenicillin, is a pro-drug that is processed to benzylpenicillin by esterases.^[1]

References

1. ^ Agersborg HPK; Batchelor, A; Cambridge, GW; Rule, AW (1966). "THE PHARMACOLOGY OF PENAMECILLIN". Brit. J. Pharmacol. 26 (3): 649–55. PMC 1510697. PMID 4959939. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1510697. 

v t e Antibacterials: cell envelope antibiotics (J01C-J01D) Intracellular inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin) DADAL/AR inhibitors (Cycloserine) bactoprenol inhibitors (Bacitracin) Glycopeptide inhibit PG chain elongation: Vancomycin# (Oritavancin Telavancin) Teicoplanin (Dalbavancin) Ramoplanin β-lactams/ (inhibit PBP cross-links) Penicillins (penams) Extended sp. aminopenicillins: Amoxicillin# Ampicillin# (Pivampicillin Hetacillin Bacampicillin Metampicillin Talampicillin) Epicillin carboxypenicillins: Carbenicillin (Carindacillin) Ticarcillin Temocillin ureidopenicillins: Azlocillin Piperacillin Mezlocillin other: Mecillinam (Pivmecillinam) Sulbenicillin Narrow sp. β-lactamase sensitive Benzylpenicillin (G)#: Clometocillin Benzathine benzylpenicillin# Procaine benzylpenicillin# Azidocillin Penamecillin Phenoxymethylpenicillin (V)#: Propicillin Benzathine phenoxymethylpenicillin Pheneticillin β-lactamase resistant Cloxacillin# (Dicloxacillin Flucloxacillin) Oxacillin Meticillin Nafcillin Penems Faropenem Carbapenems Biapenem Ertapenem antipseudomonal (Doripenem Imipenem Meropenem) Panipenem Cephalosporins/Cephamycins (cephems) 1st (PEcK) Cefazolin# Cefacetrile Cefadroxil Cefalexin Cefaloglycin Cefalonium Cefaloridine Cefalotin Cefapirin Cefatrizine Cefazedone Cefazaflur Cefradine Cefroxadine Ceftezole 2nd (HEN) Cefaclor Cefamandole Cefminox Cefonicid Ceforanide Cefotiam Cefprozil Cefbuperazone Cefuroxime Cefuzonam cephamycin (Cefoxitin Cefotetan Cefmetazole) carbacephem (Loracarbef) 3rd Cefixime# Ceftriaxone# antipseudomonal (Ceftazidime# Cefoperazone) Cefcapene Cefdaloxime Cefdinir Cefditoren Cefetamet Cefmenoxime Cefodizime Cefotaxime Cefpimizole Cefpiramide Cefpodoxime Cefsulodin Cefteram Ceftibuten Ceftiolene Ceftizoxime oxacephem (Flomoxef Latamoxef ‡) 4th (antips-) Cefepime Cefozopran Cefpirome Cefquinome 5th Ceftobiprole Ceftaroline fosamil Veterinary Ceftiofur Cefquinome Cefovecin Monobactams Aztreonam Tigemonam Carumonam Nocardicin A β-lactamase inh. penam (Sulbactam Tazobactam) clavam (Clavulanic acid) Combinations Amoxicillin/clavulanic acid# Imipenem/cilastatin# Ampicillin/flucloxacillin Ampicillin/sulbactam (Sultamicillin) Piperacillin/tazobactam Other polymyxins/detergent (Colistin Polymyxin B) depolarizing (Daptomycin) hydrolyze NAM-NAG (Lysozyme) Gramicidin #WHO-EM ‡Withdrawn from market Clinical trials: †Phase III §Never to phase III M: BAC bact (clas) gr+f/gr+a(t)/gr-p(c)/gr-o drug(J1p, w, n, m, vacc)

This systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it. v t e

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)