Peplomer

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a virus-coded proteinaceous knob or spike, numbers of which project from the peplos (i.e., envelope (def. 3)) of an enveloped virus particle. Peplomers may have cell-receptor, hemagglutinating, or neuramidinase activity.

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A glycoprotein structural unit found in the lipoprotein envelope of enveloped viruses, e.g. H and N spikes of influenza virus. Called also spikes.

A peplomer is a glycoprotein spike on a viral capsid or viral envelope.[1] These protrusions will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together.

The tail fibers of some bacteriophages, especially the T4-like phages, are modified peplomers.

See also

References

  1. ^ Saunders Comprehensive Veterinary Dictionary (3rd ed.). Elsevier, Inc. 2007.  as cited in "peplomer". The Free Dictionary. Farlex. 2011. http://medical-dictionary.thefreedictionary.com/peplomer. Retrieved 30 Mar 2011. 



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