Pericentriolar material (PCM) is an amorphous mass of protein which makes up the part of the animal centrosome that surrounds the two centrioles. The PCM contains proteins responsible for microtubule nucleation and anchoring[1] including γ-tubulin, pericentrin and ninein.
According to the Gene Ontology, the following human proteins are associated with the PCM [1]:
- BBS4, Bardet-Biedl syndrome 4 protein
- Lck, Proto-oncogene tyrosine-protein kinase LCK
- PCM1, Pericentriolar material 1 protein
- TNKS, Tankyrase-1
- TNKS2, Tankyrase-2
- TUBE1, Tubulin epsilon chain
References
- ^ Eddé, B; Rossier; Le Caer; Desbruyères; Gros; Denoulet (1990). "Posttranslational glutamylation of alpha-tubulin". Science 247 (4938): 83–5. Bibcode 1990Sci...247...83E. doi:10.1126/science.1967194. PMID 1967194.
|
||||||||||||||
 |
This cell biology article is a stub. You can help Wikipedia by expanding it. |
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
