Pertactin
Oxford Dictionary of Biochemistry:
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pertactin
other name: outer membrane protein P68; an agglutinogen of Bordetella spp. that binds to eukaryotic cells, and is involved in the pathogenicity in whooping cough. It contains the RGD sequence motif.
| perspective formula, persephin, perseitol | |
| perturb, perturbant, perturbation |
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Pertactin
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| Pertactin | |||||||||
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| Identifiers | |||||||||
| Symbol | |||||||||
| Pfam | PF03212 | ||||||||
| InterPro | IPR004899 | ||||||||
| PROSITE | PDOC00271 | ||||||||
| SCOP | 1dab | ||||||||
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Pertactin (PRN) is a highly immunogenic virulence factor of Bordetella pertussis, a bacterium that causes pertussis. Specifically, it is an outer membrane protein that promotes adhesion to tracheal epithelial cells. PRN is purified from Bordetella pertussis and is used for the vaccine production as one of the important components of acellular pertussis vaccine.[citation needed]
Pertactin domains are common components of the excreted portion of bacterial autotransporter proteins. The domain is made up of a beta helix of variable length.
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Oxford Dictionary of Biochemistry
Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.
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