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Phendimetrazine

 
Drug Info: Phendimetrazine
 

Brand names: Bock-Arate™Bontril®Bontril® PDMBontril® SRKraft-Pleg™Kraft-Stat 35™Melfiat®Prelu-2®Rapdone™

Chemical formula:



Phendimetrazine Tartrate Oral tablet

What is this medicine?

PHENDIMETRAZINE decreases your appetite. It is used with a reduced calorie diet and exercise to help you lose weight.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
•agitation or nervousness
•glaucoma
•heart disease
•high blood pressure
•history of substance abuse
•thyroid disease
•an unusual or allergic reaction to phendimetrazine, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine at least 1 hour before eating. Do not take your medicine more often than directed. Do not suddenly stop taking your medicine because you may develop a severe reaction. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
•MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
•medicines for colds or breathing difficulties like pseudoephedrine or phenylephrine
•procarbazine
•sibutramine
•stimulants like dexmethylphenidate, methylphenidate or modafinil

This medicine may also interact with the following medications:
•medicines for diabetes
•medicines for high blood pressure

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Notify your physician immediately if you become short of breath while doing your normal activities.

This medicine was intended to be used in addition to a healthy diet and exercise. The best results are achieved this way. This medicine is only indicated for short-term use. Eventually your weight loss may level out. At that point, the drug will only help you maintain your new weight. Do not increase or in any way change your dose without consulting your doctor.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
•chest pain, palpitations
•depression or severe changes in mood
•increased blood pressure
•irritability
•nervousness or restlessness
•painful urination
•severe dizziness
•vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•blurred vision or other eye problems
•changes in sexual ability or desire
•constipation or diarrhea
•difficulty sleeping
•dry mouth
•flushing
•headache
•nausea
•sweating

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

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Wikipedia: Phendimetrazine
 
Phendimetrazine
Systematic (IUPAC) name
3,4-Dimethyl-2-phenyl-morpholine
Identifiers
CAS number 634-03-7
ATC code  ?
PubChem 12460
Chemical data
Formula C12H17NO 
Mol. mass 191.27
Pharmacokinetic data
Bioavailability Peak plasma levels occur within 1 to 3 hours. Absorption is usually complete by 4 to 6 hours
Metabolism hepatic
Half life 19-24 hours
Excretion Urinary elimination
Therapeutic considerations
Pregnancy cat.

C (US)

Legal status

C-III (US)

Routes Oral

Phendimetrazine (Bontril) is a weight loss medication.[1]

Contents

Pharmacology

Phendimetrazine is used clinically in the form of phendimetrazine tartrate.

Approximately 30% of a given dose of phendimetrazine is metabolized into phenmetrazine, which may account for part of its anorectic effect, and probably also influences abuse potential; individuals who metabolise a greater proportion of phendimetrazine into phenmetrazine are more likely to develop problems with dependence and addiction.

Commercial trade names

  • Adipost
  • Anorex-SR
  • Bontril PDM
  • Appecon
  • Bontril Slow-Release
  • Obezine
  • Phendiet
  • Plegine
  • Prelu-2
  • Statobex
  • Melfiat


Legal status

Phendimetrazine is a drug as potent as amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, phendimetrazine is a Schedule III controlled substance under the Uniform Controlled Substances Act of 1970.

According to the "List of psychotropic substances under international control," phendimetrazine is a Schedule IV controlled substance.[2] Phendimetrazine is listed as a Schedule III substance under the U.S. Controlled Substance Act in the 2007 Drug Identification Bible, pg 615 and under Section 11056(b)(6) California Health and Safety Code.

References

External links


 
 

 

Copyrights:

Drug Info. Gold Standard. Copyright © 2008 by Gold Standard. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phendimetrazine" Read more