Phosphoethanolamine N-methyltransferase

In enzymology, a phosphoethanolamine N-methyltransferase (EC 2.1.1.103) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + ethanolamine phosphate S-adenosyl-L-homocysteine + N-methylethanolamine phosphate

Thus, the two substrates of this enzyme are S-adenosyl methionine and ethanolamine phosphate, whereas its two products are S-adenosylhomocysteine and N-methylethanolamine phosphate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase. This enzyme is also called phosphoethanolamine methyltransferase. This enzyme participates in glycerophospholipid metabolism.

References

• Datko AH and Mudd SH (1988). "Enzymes of phosphatidylcholine synthesis in Lemna, soybean, and carrot". Plant Physiol. 88: 1338–1348. doi:10.1104/pp.88.4.1338.