Phosphoglycerate kinase

An enzyme which catalyzes the transfer of high-energy phosphate to ADP.

phosphoglycerate kinase 1 Enzyme Phosphoglycerate kinase PDB Code PDB 3PGK Organism Yeast Symbol(s): PGK1 Genetic data Locus: Chr. X q13.3 Database Links EC number: 2.7.2.3 Entrez: 5230 OMIM: 311800 RefSeq: NM_000291 UniProt: P00558

phosphoglycerate kinase 2 Symbol(s): PGK2 Genetic data Locus: Chr. 6 p21-q12 Database Links Entrez: 5232 OMIM: 172270 RefSeq: NM_138733 UniProt: P07205

Phosphoglycerate kinase is a transferase enzyme used in the seventh step of glycolysis.

It transfers a phosphate group from 1,3-biphosphoglycerate to ADP, forming ATP and 3-Phosphoglycerate.

1,3-Bisphosphoglycerate

Glycerate 3-phosphate

External links

• -858783685 at GPnotebook
• MeSH Phosphoglycerate+kinase
• Illustration at arizona.edu

This article about metabolism is a stub. You can help Wikipedia by expanding it. v • d • e

v • d • e Glycolysis Metabolic Pathway

Glucose Hexokinase Glucose 6-phosphate Glucose-6-phosphate isomerase Fructose 6-phosphate phosphofructokinase-1 Fructose 1,6-bisphosphate Fructose bisphosphate aldolase ATP ADP ATP ADP Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde-3-phosphate dehydrogenase 1,3-Bisphosphoglycerate NAD+ + Pi NADH + H+ + 2 2 Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Phosphopyruvate hydratase(Enolase) Phosphoenolpyruvate Pyruvate kinase Pyruvate ADP ATP H2O ADP ATP 2 2 2 2 see also disorders

v • d • e Metabolism: carbohydrate metabolism: glycolysis/gluconeogenesis enzymes Glycolysis Hexokinase (HK1, HK2, HK3, Glucokinase)→/Glucose 6-phosphatase← · Glucose isomerase · Phosphofructokinase 1 (Liver, Muscle, Platelet)→/Fructose 1,6-bisphosphatase← Aldolase (A, B)  · Triosephosphate isomerase Glyceraldehyde 3-phosphate dehydrogenase · Phosphoglycerate kinase · Phosphoglycerate mutase · Enolase · Pyruvate kinase (PKLR, PKM2) Gluconeogenesis only to oxaloacetate: Pyruvate carboxylase · Phosphoenolpyruvate carboxykinase from lactate (Cori cycle): Lactate dehydrogenase from alanine (Alanine cycle): Alanine transaminase from glycerol: Glycerol kinase · Glycerol dehydrogenase Regulatory Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase (PFKFB1, PFKFB2, PFKFB3, PFKFB4) · Bisphosphoglycerate mutase see also disorders, intermediates

v • d • e Transferases: Phosphotransferases/kinases (EC 2.7) 2.7.1: OH acceptor Hexo- · Gluco- · Fructo- (Hepatic) · Galacto- · Phosphofructo- (1, Liver, Muscle, Platelet, 2) · Riboflavin · Shikimate · Thymidine (ADP-thymidine) · NAD+ · Glycerol · Pantothenate · Mevalonate · Pyruvate · Deoxycytidine · PFP · Diacylglycerol · Bruton's tyrosine · Phosphoinositide 3 (Class I PI 3, Class II PI 3) · Sphingosine · Glucose-1,6-bisphosphate synthase 2.7.2: COOH acceptor Phosphoglycerate · Aspartate 2.7.3: N acceptor Creatine 2.7.4: PO4 acceptor Phosphomevalonate · Adenylate · Nucleoside-diphosphate 2.7.6: P2O7 Ribose-phosphate diphosphokinase · Thiamine pyrophosphokinase 2.7.7: nucleotidyl- Polymerase DNA polymerase DNA-directed DNA polymerase: DNA polymerase I · DNA polymerase II · DNA polymerase III holoenzyme · Reverse transcriptase (Telomerase) DNA nucleotidylexotransferase/Terminal deoxynucleotidyl transferase RNA nucleotidyltransferase RNA polymerase/DNA-directed RNA polymerase: RNA polymerase I · RNA polymerase II · RNA polymerase III · RNA polymerase IV · Primase · RNA-dependent RNA polymerase PNPase Other Recombinase (Integrase) · RNase PH · UDP-glucose pyrophosphorylase · Galactose-1-phosphate uridylyltransferase · Transposase 2.7.8: other phos. N-acetylglucosamine-1-phosphate transferase 2.7.10-11: protein Tyrosine · Serine/threonine-specific 2.7.12: dual-specificity Dual-specificity kinase · Mitogen-activated protein kinase kinase 2.7.13 protein-histidine Protein-histidine pros-kinase · Protein-histidine tele-kinase · Histidine kinase

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