Picotamide
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Picotamide
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| Systematic (IUPAC) name | |
| 4-methoxy-N,N'-bis(pyridin-3-ylmethyl)isophthalamide | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| ATC code | B01AC03 |
| PubChem | CID 4814 |
| ChemSpider | 4649  |
| UNII | 654G2VCI4Q |
| Chemical data | |
| Formula | C21H20N4O3 |
| Mol. mass | 376.409 g/mol |
| SMILES | eMolecules & PubChem |
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Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor.[1]
References
- ^ Ratti, S; Quarato, P; Casagrande, C; Fumagalli, R; Corsini, A (1998). "Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes". European Journal of Pharmacology 355 (1): 77–83. doi:10.1016/S0014-2999(98)00467-1. PMID 9754941.
External links
- Andrea Celestini and Francesco Violi: A review of picotamide in the reduction of cardiovascular events in diabetic patients (PubMed)
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