Pindone

pindone

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One of a series of 2-aryl-1,3-indandiones which have potent anticoagulant activity. Can cause fatal hemorrhage in animals.

Pindone

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Pindone

IUPAC name 2-(2,2-Dimethyl-1-oxopropyl)indane-1,3-dione
Other names 2-Pivaloyl-1,3-indandione
Identifiers
CAS number	83-26-1^N
PubChem	6732
ChemSpider	6476^Y
KEGG	C19141^N
Jmol-3D images	Image 1
SMILES O=C2c1ccccc1C(=O)C2C(=O)C(C)(C)C
InChI InChI=1S/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3^Y Key: RZKYEQDPDZUERB-UHFFFAOYSA-N^Y InChI=1/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3 Key: RZKYEQDPDZUERB-UHFFFAOYAX
Properties
Molecular formula	C₁₄H₁₄O₃
Molar mass	230.26 g/mol
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pindone is an anticoagulant drug^[1] for agricultural use. It is commonly used as a rodenticide in the management of rat and rabbit populations.

It is pharmacologically analogous to warfarin and inhibits the synthesis of Vitamin K-dependent clotting factors.

References

^ Robinson MH, Twigg LE, Wheeler SH, Martin GR (March 2005). "Effect of the anticoagulant, pindone, on the breeding performance and survival of merino sheep, Ovis aries". Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 140 (3): 465–73. doi:10.1016/j.cbpc.2004.11.011. PMID 15694595. http://linkinghub.elsevier.com/retrieve/pii/S1096-4959(04)00377-X.

v t e Pest control: rodenticides

Anticoagulants/ vitamin K antagonists	coumarins/4-Hydroxycoumarins: 1st generation (Warfarin, Coumatetralyl) • 2nd generation (Brodifacoum, Difenacoum, Flocoumafen) 1,3-Indandiones: Chlorophacinone • Pindone • Diphacinone other: Difethialone

Convulsants	Crimidine • Phenylsilatrane • Strychnine • Tetramethylenedisulfotetramine

Calciferols	Cholecalciferol • Ergocalciferol

Inorganic compounds	Aluminium phosphide • Arsenic • Barium carbonate • Calcium phosphide • Cyanide • Thallium • Zinc phosphide

Organochlorine	Chloralose • Endrin

Organophosphorus	Phosacetim

Metabolic poisons	Bromethalin • Fluoroacetamide • 1,3-Difluoro-2-propanol (Gliftor) • Sodium fluoroacetate

Other	α-Naphthylthiourea • Norbormide • Pyrinuron • Scilliroside

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