A plasminogen activator is a serine protease which converts plasminogen to plasmin, thus promoting fibrinolysis.
Types include:
It is inhibited by Plasminogen activator inhibitor-1 and Plasminogen activator inhibitor-2
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Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21) |
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| Digestive enzymes |
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| Coagulation |
factors: Thrombin · Factor VIIa · Factor IXa · Factor Xa · Factor XIa · Factor XIIa · Kallikrein ( PSA, KLK1, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9, KLK10, KLK11, KLK12, KLK13, KLK14, KLK15)
fibrinolysis: Plasmin · Plasminogen activator ( Tissue plasminogen activator · Urinary plasminogen activator)
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| Complement system |
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| Other immune system |
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| Venombin |
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| Other |
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Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01) |
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| Antiplatelet drugs |
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| Anticoagulants |
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Factor Xa inhibitors
(with some II inhibition)
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low molecular weight heparin ( Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin)
oligosaccharides (Fondaparinux, Idraparinux)
heparinoid ( Danaparoid, Sulodexide, Dermatan sulfate)
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Other
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Thrombolytic drugs/
fibrinolytics |
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| Non-medicinal |
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