polyglutamine
Oxford Dictionary of Biochemistry:
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polyglutamine
or (sometimes) polyglutamine tract
a stretch of amino acids in a protein that is entirely composed of glutamine. Gene sequences giving rise to this structure may have (CAG)n repeats and can be subject to replication slippage. A consequence is expansion of polyglutamine tracts in succeeding generations eventually causing symptoms of disease. Huntingtin is a well-known example. See Huntington's disease.
a stretch of amino acids in a protein that is entirely composed of glutamine. Gene sequences giving rise to this structure may have (CAG)n repeats and can be subject to replication slippage. A consequence is expansion of polyglutamine tracts in succeeding generations eventually causing symptoms of disease. Huntingtin is a well-known example. See Huntington's disease.
| polyglucosan, polygenic, polygene | |
| polyglutamine disease, polygon, polyhedron |
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Oxford Dictionary of Biochemistry
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