Polyhexanide

Polyhexanide
Other names Polyhexamethylene biguanide; Polyhexamethylene guanide; Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene); Poly(hexamethylenebiguanide); Polihexanide
Identifiers
Abbreviations	PHMB
CAS number	28757-47-3 N, 32289-58-0 (HCl) Y, 28757-48-4
UNII	322U039GMF Y
ATC code	D08AC05
Properties
Molecular formula	(C8H17N5)n
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use^[1] it is spelled polihexanide (INN) and sold under names such as Lavasept and Serasept.^[2]

Some products containing PHMB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.^[3]

Branded as Baquacil, it also has an application as a swimming-pool sanitizer in place of chlorine- or bromine-based products.

Polyhexanide is used as an ingredient in some eye drops for use with contact lenses.

See also

• Polyaminopropyl biguanide, a related biguanide disinfectant

References

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