positional cloning

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(pə¦zish·ən·əl ′klon·iŋ)

(genetics) The identification of a gene and its isolation as a cloned deoxyribonucleic acid fragment, starting from knowledge of its position on a genetic map or chromosome.


Gale Genetics Encyclopedia:

positional cloning

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The use of polymorphic genetic markers ever closer to the unknown gene to track its inheritance in CF families.

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