Posizolid
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Posizolid
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| Systematic (IUPAC) name | |
| (5R)-3-[4-[1-[(2S)-2,3-Dihydroxypropanoyl]-3,6-dihydro-2H-pyridin-4-yl]-3,5-difluorophenyl]-5-(1,2-oxazol-3-yloxymethyl)-1,3-oxazolidin-2-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 252260-02-9 |
| ATC code | None |
| PubChem | CID 213049 |
| UNII | 82V2M8K24R  |
| Synonyms | AZD2563 |
| Chemical data | |
| Formula | C21H21F2N3O7 |
| Mol. mass | 465.40 g/mol |
| SMILES | eMolecules & PubChem |
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Posizolid is an oxazolidinone antibiotic under investigation by AstraZeneca for the treatment of bacterial infections. At a concentration of 2 mg/L it inhibited 98% of all Gram-positive bacteria tested in vitro.[1]
References
- ^ Wookey, A.; Turner, P. J.; Greenhalgh, J. M.; Eastwood, M.; Clarke, J.; Sefton, C. (2004). "AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on activity in vitro". Clinical Microbiology and Infection 10 (3): 247–254. doi:10.1111/j.1198-743X.2004.00770.x. PMID 15008947.
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