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Atropine and pralidoxime chloride

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Atropine and pralidoxime chloride

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Atropine is combined with pralidoxime chloride to counteract organophosphate poisoning (used in some but not all modern nerve agents as well as insectocides).

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The ATNAA kit is provided solely to active military personnel where the therat of chemical warfare exists. It is used used exclusively for acute organophosphate (OP) poisoning. The active ingredients are atropine and Pralidoxime chloride in both the Mark 1 and ATNAA kits.

Organophosphates are used mostly as insecticides, but are also the basis for Schrader's "G" class nerve agents, including Sarun and Tabun, amongst others, produced during WW-II. Later, the British produced VX -- another organophosphate. Insecticides include DDT, malthion and hexacholr amongst others.

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The NAAK contains autoinjectors of atropine and pralidoxime. The are antagonists of the actions of GA, GB, GD and VX nerve agents. VX, for example, is an organophosphate (also used as an insect toxin). It is an acetylcholinesterase (ACE) inhibitor. The body secretes ACE to "turn off" muscles by dissolving acetylcholine, the conductor that makes muscles contract.

ACE inhibitor toxins work by causing supercontractions of the muscles, most notably the diaphragm. This causes death by asphyxia.

Prompt delivery of the contents of the NAAK may stave off the effects of these chemical agents.

Note that the NAAK is ineffective against other agents like chlorine gas.

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There is a kit Called Mark I. It is carried by Paramedics and military medics mainly after sept 11, 2001. It is in the form of a autoinjection pen sort of like the epi pens carried by people with extreme allergies (bee stings, Peanuts ect...) There are two drugs. the first drug is atropine. Atropine works on the body to dry up the secretions caused by . the nerve agent. the second drug is pralidoxime chloride that helps the body block the nerve agent

you would also want a anti convulsant on hand. Versed is a strong benzo that is perferred. I hope that answed your question. I am a Paramedic that has recieved extensive training in nerve agens since that dreaded day in 2001. Good luck

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