Pramocaine

Pramocaine

Systematic (IUPAC) name
4-[3-(4-butoxyphenoxy)propyl]morpholine
Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a682429
Pregnancy cat.	?
Legal status	POM (UK) ℞-only (US) (with hydrocortisone)
Routes	Topical, rectal
Identifiers
CAS number	140-65-8 N 637-58-1
ATC code	D04AB07 C05AD07
PubChem	CID 4886
ChemSpider	4717 Y
UNII	068X84E056 Y
ChEBI	CHEBI:8357 Y
ChEMBL	CHEMBL1198 Y
Chemical data
Formula	C17H27NO3
Mol. mass	293.401 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C17H27NO3/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18/h5-8H,2-4,9-15H2,1H3 Y Key:DQKXQSGTHWVTAD-UHFFFAOYSA-N Y
N (what is this?)  (verify)

Pramocaine (INN and BAN, also known as pramoxine) is a topical anesthetic used as an antipruritic.

The popular itch cream Gold Bond uses pramocaine hydrochloride to numb sensitive skin as well as does the pain relief variant of Neosporin and some formulations of Sarna. The hydrochloride salt form of pramocaine is water-soluble, and therefore more easily absorbed into the skin.

Usage

Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches.^[1]Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.

Notes

See also

• Local anesthesia