procollagen

(prō′käl·ə·jən)

(biochemistry) A high-molecular-weight form of collagen that is found in intracellular spaces and is believed to be the precursor of collagen.

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pro·col·la·gen

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(prō-kŏl'ə-jən)
n.

The soluble precursor of collagen possibly formed by fibroblasts in the process of collagen synthesis.

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The precursor of collagen, synthesized in osteoblasts and fibroblasts and subsequently converted to form collagen by procollagen peptidase.

p. N-peptidase — one of the enzymes involved in the conversion of procollagen to collagen. There is inadequate activity of this enzyme in osteogenesis imperfecta, dermatosparaxis.

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