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Prokaryotic initiation factor-2

 
Wikipedia: Prokaryotic initiation factor-2
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Prokaryotic initiation factor-2 is a prokaryotic initiation factor.[1]

IF2 binds to an initiator tRNA and controls the entry of that tRNA into the ribosome. IF2, bound to GTP, binds to the 30S P site. After associating with the 30S subunit, fMet-tRNAf binds to the IF2 then IF2 transfers the tRNA into the partial P site. When the 50S subunit joins, it hydrolyzes GTP to GMP and PPi, causing a conformational change in the IF2 that causes IF2 to release and allow the 70S subunit to form.

References

  1. ^ MeSH Prokaryotic+Initiation+Factor-2
v • d • e
Protein biosynthesis: translation (prokaryotic, eukaryotic)
Ribosomal proteins
PIF-1 · PIF-2 · PIF-3
Archaeal
aIF1 aIF2 aIF5 aIF6
eIF1 (AX, AY, 1B)

eIF2 (α, β, γ)

eIF3 (A, B, C, D, F, G, H, I, J, K, M, S6)

eIF4 (A2, A3, B, E1, E2, G1, G2, G3, H)

eIF5 (A, A2, 5B)

eIF6
Prokaryotic (EF-Tu, EF-Ts, EF-G)  · Archaeal (aEF-1, aEF-2)  · Eukaryotic (EEF-1, EEF-2)
Prokaryotic · Archaeal · Eukaryotic
Other
Other concepts

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