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Prolactin receptor

 
Wikipedia: Prolactin receptor
prolactin receptor
Identifiers
Symbol PRLR
Entrez 5618
HUGO 9446
OMIM 176761
RefSeq NM_000949
UniProt P16471
Other data
Locus Chr. 5 p13-p12

The prolactin receptor—encoded by a gene on Chromosome 5p13-14—interacts with the prolactin molecule as a transmembrane receptor.

Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region.

The receptor is a cytokine receptor, and the second messenger cascade is the JAK-STAT pathway.

There may be variations among different tissue prolactin receptors.

See also

External links



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Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Prolactin receptor" Read more