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Prolintane

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Prolintane
Systematic (IUPAC) name
1-(1-benzylbutyl)pyrrolidine
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 493-92-5
ATC code N06BX14
PubChem CID 14592
ChemSpider 13930 YesY
UNII EM4YZW677H YesY
Chemical data
Formula C15H23N 
Mol. mass 217.35 g/mol
SMILES eMolecules & PubChem
 YesY (what is this?)  (verify)

Prolintane (Catovit) is a stimulant[1] of norepinephrine-dopamine reuptake inhibitors developed in the 1950s[2] which is closely related in chemical structure to other drugs such as pyrovalerone and MDPV, and with a similar mechanism of action. It is a mild stimulant with a very good safety profile.[3] The good safety profile of this drug makes it suitable for use in elderly people to increase motivation and counteract the effects of senile dementia and age-related cognitive decline.[4] It is mainly used in European countries. Anecdotally cases of prolintane abuse have been reported.[5][6][7]

See also

References

  1. ^ Hollister, L. E.; Gillespie, H. K. (1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of Clinical Pharmacology 10 (2): 103–109. doi:10.1177/009127007001000205. PMID 4392006.  edit
  2. ^ GB Patent 807835
  3. ^ Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). "Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline". British Journal of Clinical Pharmacology 10 (5): 465–472. PMC 1430138. PMID 7437258. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1430138.  edit
  4. ^ Kuitunen, T.; Kärkkäinen, S.; Ylitalo, P. (1984). "Comparison of the acute physical and mental effects of ephedrine, fenfluramine, phentermine and prolintane". Methods and Findings in Experimental and Clinical Pharmacology 6 (5): 265–270. PMID 6471970.  edit
  5. ^ Payá, B.; Guisado, J. A.; Vaz, F. J.; Crespo-Facorro, B. (2002). "Visual Hallucinations Induced by the Combination of Prolintane and Diphenhydramine". Pharmacopsychiatry 35 (1): 24–25. doi:10.1055/s-2002-19829. PMID 11819155.  edit
  6. ^ Gaulier, J. M.; Canal, M.; Pradeille, J. L.; Marquet, P.; Lachâtre, G. (2002). "New Drugs at “rave parties”: Ketamine and Prolintane". Acta Clinica Belgica. Supplementum (1): 41–46. PMID 11974443.  edit
  7. ^ Kyle, P. B.; Daley, W. P. (2007). "Domestic Abuse of the European Rave Drug Prolintane". Journal of Analytical Toxicology 31 (7): 415–418. PMID 17725890.  edit
Psychostimulants, agents used for ADHD, and nootropics (N06B)
Centrally acting sympathomimetics
Xanthine derivatives
Glutamate receptor
CX-516 • CX-546 • CX-614 • CX-691 • CX-717 • IDRA-21 • LY-404,187 • LY-503,430 • PEPA • S-18986 • Sunifiram • Unifiram
Eugeroics / Benzhydryl compounds
Histamine H3 receptor antagonists
GABAA α5 inverse agonists
Dopamine D1 receptor agonists
α7 nicotinic agonists / PAMs
Prolyl endopeptidase inhibitors
Alpha-adrenergic agonists
Plants
Antioxidants
Stabilized R-(+)-lipoic acid (RLA)
Other psychostimulants and nootropics

M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc(eval/thrp), drug(N5A/5B/5C/6A/6B/6D)


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