promethazine hydrochloride

One of the original (sedating) antihistamines, used to relieve the symptoms of such allergic conditions as hay fever and urticaria. It is also used as an antiemetic and as a hypnotic drug for the short-term treatment of insomnia. Promethazine is available as tablets or an elixir that can be bought from pharmacies without a prescription, and as a solution for injection on prescription only.

Side effects:
see antihistamines; promethazine may also cause extrapyramidal reactions.

Precautions and interactions with other drugs:
see antihistamines.

Proprietary preparations:
Phenergan; Sominex (tablets for insomnia); Day and Night Nurse (combined with paracetamol, pseudoephedrine, pholcodine, and dextromethorphan); Medised (combined with paracetamol); Night Nurse (combined with paracetamol and dextromethorphan); Pamergan P100 (combined with pethidine); Tixylix Night Cough (combined with pholcodine).

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