Share on Facebook Share on Twitter Email
Answers.com

Prostaglandin analogue

 
Medical Glossary: Prostaglandin analogue
Home > Library > Health > Medical Glossary

A class of drugs that are similar in structure and function to prostaglandin.

Search unanswered questions...

Enter a question here...
Search: All sources Community Q&A Reference topics

Wikipedia: Prostaglandin analogue
Top
Home > Library > Miscellaneous > Wikipedia

Synthetic prostaglandin analogues are molecules which are manufactured to bind to a prostaglandin receptor.

Wider use of prostaglandin analogues is limited by unwanted side effects and their abortive potential.

Uses

  • Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. They exert antisecretory and cytoprotective properties and are especially indicated for the elderly on continuous doses of NSAIDs.
  • Prostaglandin analogues can also be used in the management of open-angle glaucoma. They reduce intra-ocular pressure by enhancing uveoscleral outflow and may also have some effect on the trabecular meshwork as well. Latanoprost, travoprost, unoprostone and bimatoprost are examples of prostaglandin analogues used in the management of open-angle glaucoma. In some countries such as Australia, they are now considered first line agents in open-angle glaucoma (rather than beta blockers)[1]

References

  1. ^ AMH 2008: Australian Medicines Handbook, 9th Edition Adelaide, S. Aust. : Australian Medicines Handbook, c2008.,

External links

v • d • e
Drugs for acid related disorders: Drugs for peptic ulcer and GERD/GORD (A02B)
H2 antagonists ("-idine")
Prostaglandins (E)/analogues ("-prost-")
Proton pump inhibitors ("-prazole")
Other
v • d • e
Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)
Antiplatelet drugs
ADP receptor/P2Y12 inhibitors
Prostaglandin analogue (PGI2)
Other
Anticoagulants
Factor Xa inhibitors
(with some II inhibition)
Other
Thrombolytic drugs/
fibrinolytics
Non-medicinal
Citrate • EDTA • Oxalate
#WHO-EM. †Undergoing clinical trials, not FDA approved. ‡Withdrawn from market. §Development halted.
v • d • e
Oxytocics (G02A)
Ergot alkaloids
Prostaglandins (E/F)
Dinoprost · Dinoprostone · Prostaglandin analogues (Gemeprost, Carboprost, Sulprostone, Misoprostol#)
Other
#WHO-EM. †Undergoing clinical trials, not FDA approved. ‡Withdrawn from market. §Development halted.
v • d • e
Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics
Parasympathomimetics
muscarinic/nicotinic
Carbonic anhydrase inhibitors/
(sulfonamides)
Beta blocking agents
Prostaglandin analogues (F2α)
Other agents
v • d • e
Autacoids, unsaturated fatty acids: Eicosanoids
Precursor
Prostanoids
Prostaglandins (PG) and
analogues
Precursor
Active
D/J
E/F
I
A2 · B2
Leukotrienes (LT)
Precursor
Initial
A4 · B4
C4 · D4 · E4
Nonclassic
By function
bronchoconstriction (PGF2α, TXA2, LTC4, LTD4, LTE4)

vasoconstriction (PGF2α, TXA2, TXB2) · vasodilation (PGE2, PGI2, LTC4, LTD4, LTE4)

platelets: induce (TXA2) inhibit (PGD2, PGI2) · leukocytes: induce (TXA2, LTB4) inhibit (PGD2, PGE2)

labor stimulation: (PGE2 (Dinoprostone), PGF2α (Dinoprost))
see also enzymes


Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)

 
 

 

Copyrights:

Medical Glossary. © 2006 through a partnership of Answers Corporation. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Prostaglandin analogue".  Read more