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Medical Glossary:

Prostaglandin analogue

A class of drugs that are similar in structure and function to prostaglandin.

 
 
Wikipedia: prostaglandin analogue

Synthetic prostaglandin analogues are molecules which are manufactured to bind to a prostaglandin receptor.

Wider use of prostaglandin analogues is limited by unwanted side effects and their abortive potential.

Uses

  • Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. They exert antisecretory and cytoprotective properties and are especially indicated for the elderly on continuous doses of NSAIDs.
  • Prostoglandin analogues can also be used in the management of open-angle glaucoma. They reduce intra-ocular pressure by enhancing uveoscleral outflow and may also have some effect on the Trabecular meshwork as well. Latanoprost is the main Prostoglandin analogue used in the management of Open-Angle Glaucoma

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