Prostaglandin E is a family of naturally occurring prostaglandins and may be used pharmaceutically in medicine.
Types include:
- Prostaglandin E1 also termed Alprostadil
- Prostaglandin E2 also termed Dinoprostone
It is created from prostaglandin E synthase.
Prostaglandin E2
Prostaglandin E2 is secreted in microvessels by the endothelium. It is a direct vasodilator and it inhibits the release of noradrenaline from sympathetic nerve terminals. It doesn't have the effect on platelets PGI2 does.
References
Pharmacology 2007. Rang, Dale, Ritter, Flower. Churchill Livingstone Elsevier.
External links
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