Protein nitrogen unit
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Protein nitrogen unit
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The protein nitrogen unit (PNU) measures the potency of the compounds used in allergy skin tests, and is equivalent to 0.01 microgram (µg) of phosphotungstic acid-precipitable protein nitrogen.[1]
According to Russ Rowlett at the University of North Carolina at Chapel Hill,[2]
Unfortunately, the potency measurements depend on the technique of measurement used, so results of one manufacturer are not comparable to those of another manufacturer. As a result, although PNU's are still used, they are being replaced by bioequivalent allergy units (BAU), which are measured by actual skin testing using reference preparations of standard potency.
Notes
- ^ May, JC; Sih, JT et al.; Best, J; Douglas, G; Rancour, JM; Renker, HR; Spingola, F; Van Daele, L et al. (November 1981). "Protein nitrogen unit precipitation procedure for allergenic extracts: collaborative study". J Assoc off Anal Chem 64 (6): 1435–8. PMID 7309663. Site is an abstract provided by PubMed
- ^ Ross, Rowlett (2002). "P". How Many? A Dictionary of Units of Measurement. University of North Carolina at Chapel Hill. http://www.unc.edu/~rowlett/units/dictP.html. Retrieved 2009-02-05.
The end product of protein nitrogen in man is Urea
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