Psycholeptic: Information from Answers.com

In pharmacology, a psycholeptic is a medication which produces a calming effect upon the patient.

The psycholeptics are classified under N05 in the Anatomical Therapeutic Chemical Classification System.

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v • d • e Pharmacology: Major drug groups

Gastrointestinal tract/metabolism (A)	stomach acid (Antacids, H₂ antagonists, Proton pump inhibitors) • Antiemetics • Laxatives • Antidiarrhoeals/Antipropulsives • Anti-obesity drugs • Anti-diabetics • Vitamins • Dietary minerals

Blood and blood forming organs (B)	Antithrombotics (Antiplatelets, Anticoagulants, Thrombolytics/fibrinolytics) • Antihemorrhagics (Platelets, Coagulants, Antifibrinolytics)

Cardiovascular system (C)	cardiac therapy/antianginals (Cardiac glycosides, Antiarrhythmics, Cardiac stimulants) Antihypertensives • Diuretics • Vasodilators • Beta blockers • Calcium channel blockers • renin-angiotensin system (ACE inhibitors, Angiotensin II receptor antagonists, Renin inhibitors) Antihyperlipidemics (Statins, Fibrates, Bile acid sequestrants)

Skin (D)	Emollients • Cicatrizants • Antipruritics • Antipsoriatics • Medicated dressings

Reproductive system (G)	Hormonal contraception • Fertility agents • SERMs • Sex hormones

Endocrine system (H)	Hypothalamic-pituitary hormones • Corticosteroids (Glucocorticoids, Mineralocorticoids) • Sex hormones • Thyroid hormones/Antithyroid agents

Infections and infestations (J, P, QI)	Antibiotics (Antimycobacterials) • Antifungals • Antivirals • Antiparasitics (Antiprotozoals, Anthelmintics) • Ectoparasiticides • Intravenous immunoglobulin • Vaccines

Malignant disease (L01-L02)	Anticancer agents (Antimetabolites, Alkylating, Spindle poisons, Antineoplastic, Topoisomerase inhibitors)

Immune disease (L03-L04)	Immunomodulators (Immunostimulants, Immunosuppressants)

Muscles, bones, and joints (M)	Anabolic steroids • Anti-inflammatories (NSAIDs) • Antirheumatics • Corticosteroids • Muscle relaxants • Bisphosphonates

Brain and nervous system (N)	Anesthetics (General, Local) • Analgesics • Antimigraines • Anticonvulsants/Mood stabilizers (Lithium pharmacology) • Antiparkinson drugs Psycholeptics (Anxiolytics, Antipsychotics, Hypnotics/Sedatives) • Psychoanaleptics (Antidepressants, Stimulants)

Respiratory system (R)	Decongestants • Bronchodilators • Cough medicines • H₁ antagonists

Sensory organs (S)	Ophthalmologicals • Otologicals

Other ATC (V)	Antidotes • Contrast media • Radiopharmaceuticals • Dressings

Psycholeptics: antipsychotics (N05A)

Typicals

Phenothiazines	Chlorpromazine^# • Fluphenazine^# • Mesoridazine • Perazine • Periciazine • Perphenazine • Prochlorperazine • Promazine • Thioridazine/Sulforidazine • Trifluoperazine • Triflupromazine

Butyrophenones	Haloperidol^# • Azaperone • Benperidol • Bromperidol • Droperidol • Fluanisone • Trifluperidol

Indoles	Molindone

Thioxanthenes	Flupentixol • Chlorprothixene • Thiothixene • Zuclopenthixol

Diphenylbutylpiperidines	Fluspirilene • Penfluridol • Pimozide

Others	Amoxapine • Loxapine

Atypicals

Serotonin antagonists

D₂ selective

Butyrophenones	Melperone

Indoles	Sertindole • Ziprasidone

Other	Quinolone (Aripiprazole) • Oxepin (Asenapine) • Isoxazole (Iloperidone, Paliperidone, Risperidone) • Benzazepine (Mosapramine) • Thiazole (Perospirone) • Dibenzothiazepine (Quetiapine) • Dibenzothiepin (Zotepine) • Lurasidone^†

D₄ selective

diazepine (Clozapine, Olanzapine)

GHB receptor

D₂ selective

benzamides (Amisulpride, Sulpiride, Remoxipride)

^#WHO-EM. ^‡Withdrawn from market. CLINICAL TRIALS: ^†Phase III. ^§Never to phase III

v • d • e Psycholeptics: Anxiolytics (N05B)

GABA_A PAMs	Benzodiazepines: Adinazolam • Alprazolam • Bretazenil • Bromazepam • Camazepam • Chlordiazepoxide • Clobazam • Clonazepam • Clorazepate • Clotiazepam • Cloxazolam • Diazepam • Ethyl Loflazepate • Etizolam • Fludiazepam • Halazepam • Imidazenil • Ketazolam • Lorazepam • Medazepam • Nordazepam • Oxazepam • Pinazepam • Prazepam • Tofisopam; Carbamates: Emylcamate • Carisoprodol • Mebutamate • Meprobamate • Phenprobamate • Procymate • Tybamate; Nonbenzodiazepines: Abecarnil • Adipiplon • Alpidem • CGS-9896 • CGS-20625 • Divaplon • ELB-139 • Etifoxine • GBLD-345 • Gedocarnil • ICI-190,622 • L-838,417 • NS-2664 • NS-2710 • Ocinaplon • Pagoclone • Panadiplon • Pipequaline • RWJ-51204 • SB-205,384 • SL-651,498 • TP-003 • TP-13 • TPA-023 • Tracazolate • Y-23684 • ZK-93423; Others: Chlormezanone • Etazolate • Ethanol (Alcohol) • Kavalactones (Kava Kava) • Skullcap • Valerenic Acid (Valerian)

5-HT_1A Agonists	Azapirones: Buspirone • Gepirone • Tandospirone; Others: Flesinoxan • PRX-00023

H₁ Antagonists	Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine

CRF₁ Antagonists	Antalarmin • CP-154,526 • Pexacerfont

NK₂ Antagonists	GR-159,897 • Saredutant

MCH₁ antagonists	ATC-0175 • SNAP-94847

mGluR₂_/₃ Agonists	Eglumegad

mGluR5 NAMs	Fenobam

TSPO agonists	DAA-1097 • DAA-1106 • Emapunil • FGIN-127 • FGIN-143

Others	Benzoctamine • Carbetocin • Demoxytocin • Mephenoxalone • Oxytocin • Promoxolane • Trimetozine • WAY-267,464

Psycholeptics: Hypnotics and Sedatives (N05C)

GABA_A receptor

Barbiturates

Ultrashort-acting	Methohexital • Thiamylal • Thiopental

Short/intermediate- acting	Allobarbital • Amobarbital • Aprobarbital • Butobarbital • Pentobarbital • Secobarbital • Talbutal

Long-acting	Barbital • Mephobarbital • Phenobarbital

Ungrouped	Cyclobarbital • Ethallobarbital • Heptabarbital • Hexobarbital • Proxibarbal • Reposal • Vinylbital • Vinbarbital

Benzodiazepines

Short-acting	Brotizolam • Cinolazepam • Doxefazepam • Loprazolam • Midazolam • Triazolam

Intermediate-acting	Estazolam • Flunitrazepam • Lormetazepam • Nimetazepam • Temazepam

Long-acting	Flurazepam • Flutoprazepam • Nitrazepam • Quazepam

Dialkylphenols

Fospropofol • Propofol • Thymol

Nonbenzo-
diazepines

CL-218,872 • Eszopiclone • Indiplon • Necopidem • Pazinaclone • ROD-188 • Saripidem • Suproclone • Suriclone • SX-3228 • U-89843A • U-90042 • Zaleplon • Zolpidem • Zopiclone

Piperidinediones

Glutethimide • Methyprylon • Pyrithyldione • Piperidione

Quinazolinones

Afloqualone • Cloroqualone • Diproqualone • Etaqualone • Mebroqualone • Mecloqualone • Methaqualone • Methylmethaqualone

Neuroactive
steroids

Acebrochol • Allopregnanolone • Alphadolone • Alphaxolone • Ganaxolone • Hydroxydione • Minaxolone • Org 20599 • Tetrahydrodeoxycorticosterone

Alpha-2 adrenergic
receptor

Alpha-adrenergic agonists

4-NEMD • Clonidine • Dexmedetomidine • Lofexidine • Medetomidine • Romifidine • Tizanidine • Xylazine

Melatonin receptor

Melatonin

Agomelatine • Melatonin • Ramelteon • Tasimelteon

Histamine receptor &
Acetylcholine receptor

Antihistamines &
Anticholinergics

Amitriptyline • Dimenhydrinate • Doxylamine • Hydroxyzine • Diphenhydramine • Bromodiphenhydramine • Carbinoxamine • Doxepin • Orphenadrine • Mianserin • Mirtazapine • Nefazodone • Niaprazine • Phenyltoloxamine • Propiomazine • Pyrilamine • Scopolamine • Trazodone

GABA_B receptor /
GHB receptor

GHB Type

1,4-Butanediol • Aceburic acid • GABOB • GHB (Sodium Oxybate, Xyrem®) • GBL • gamma-Valerolactone • N-Methyl-GABA

Orexin receptors

Orexin antagonists

Almorexant • SB-334,867 • SB-408,124 • SB-649,868 • TCS-OX2-29

Other receptors/
ungrouped

Aldehydes	Acetylglycinamide chloral hydrate • Chloral hydrate • Chloralodol • Dichloralphenazone • Paraldehyde • Petrichloral

Alkynes	Centalun • Ethchlorvynol • Ethinamate • Hexapropymate • Methylpentynol

Carbamates	Meprobamate • Carisoprodol • Tybamate • Methocarbamol • Procymate

Other	2-Methyl-2-butanol • Acecarbromal • Acetophenone • Apronal • Bromides • Bromisoval • Carbromal • Chloralose • Clomethiazole • Embutramide • Etomidate • Evoxine • Fenadiazole • Gaboxadol • Loreclezole • Mephenoxalone • Sulfonmethane • Trichloroethanol • Triclofos • Valerian • Valnoctamide

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Psycholeptic

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