pyridoxal

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(pĭr'ĭ-dŏk'səl) pronunciation
n.
An aldehyde, C8H9NO3, one of several active forms of pyridoxine, important in amino acid synthesis.

[PYRIDOX(INE) + -AL3.]


(pĭr'ĭ-dŏk'səl)
n.

An aldehyde that is one of several active forms of pyridoxine and is important in amino acid synthesis.


abbr.: PL; 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridine carboxaldehyde; a compound with vitamin B6 activity.





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Pyridoxal
Identifiers
CAS number 66-72-8 YesY
65-22-5 (hydrochloride)
PubChem 1050
ChemSpider 1021 YesY
UNII 3THM379K8A YesY
DrugBank DB00147
KEGG C00250 YesY
ChEBI CHEBI:17310 YesY
ChEMBL CHEMBL102970 YesY
Jmol-3D images Image 1
Properties
Molecular formula C8H9NO3
Molar mass 167.16 g/mol
Melting point

165 °C (decomp.)

Related compounds
Related arylformaldehydes Damnacanthal

Gossypol

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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pyridoxal is one of the three natural forms of vitamin B6, along with pyridoxamine and pyridoxine (also called "pyridoxol"). All of these forms are converted in the human body into a single biologically active form, pyridoxal 5-phosphate. All three forms of vitamin B6 are heterocyclic organic compounds. Green plants are a natural source of pyridoxal, and its deficiency in the human body can lead to serious complications such as epilepsy and seizures.

There are generally three pyridoxal-phosphate (PLP) reactions: transamination, alpha elimination, and beta-elimination.

Pyridoxal is involved in what is believed to be the most ancient reaction of aerobic metabolism on Earth, about 2.9 billion years ago, a forerunner of the Great Oxidation Event[1]

References

  1. ^ "Protein Domain Structure Uncovers the Origin of Aerobic Metabolism and the Rise of Planetary Oxygen", Gustavo Caetano-Anolles et al., published in Structure; paper available from University of Illinois News Bureau, 2012.



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