Quinagolide
Oxford A-Z of Medicinal Drugs:
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quinagolide
A dopamine receptor agonist, very similar to bromocriptine, used to reduce elevated prolactin concentrations in certain types of infertility. It is available as tablets on prescription only.
Side effects:
include nausea, headache, dizziness, fatigue, loss of appetite, gastrointestinal disturbances, insomnia, oedema (swelling), flushing, nasal congestion, and low blood pressure.
Precautions:
quinagolide should not be taken by people with kidney or liver impairment and should be used with caution in those who have a history of psychiatric disorders. Women should stop taking the drug if they become pregnant.
Interactions with other drugs:
Dopamine antagonists: may reduce its effect.
Proprietary preparation:
Norprolac.
| quetiapine, Quinoderm, Qlaira | |
| quinapril, quinine, quinolones |
Wikipedia on Answers.com:
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Quinagolide
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| Systematic (IUPAC) name | |
| N,N-diethyl-N'-[(3S,4aS,10aR)-6-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-3-yl]sulfamide | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | Oral |
| Identifiers | |
| CAS number | 87056-78-8  |
| ATC code | G02CB04 |
| PubChem | CID 55645 |
| ChemSpider | 2343034  |
| UNII | 80Q9QWN15M |
| KEGG | D07217 |
| ChEMBL | CHEMBL290962 |
| Chemical data | |
| Formula | C20H33N3O3S |
| Mol. mass | 395.56 g/mol |
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Quinagolide (Norprolac) is a selective, D2 receptor agonist that is used for the treatment of elevated levels of prolactin.[1]
See also
References
- ^ Antonella Di Sarno, Maria Luisa Landi, Paolo Marzullo, Carolina Di Somma, Rosario Pivonello, Gaetana Cerbone, Gaetano Lombardi, Annamaria Colao (July 2000). "The effect of quinagolide and cabergoline, two selective dopamine receptor type 2 agonists, in the treatment of prolactinomas". Clinical Endocrinology 53 (1): 53–60. doi:10.1046/j.1365-2265.2000.01016.x. http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2265.2000.01016.x/full.
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