Quinapril

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Drug Info:

Quinapril

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Brand names: Accupril®

Chemical formula:



Quinapril tablets

What are quinapril tablets?

QUINAPRIL (Accupril®) is an antihypertensive (blood pressure lowering agent) known as an ACE inhibitor. Quinapril controls high blood pressure (hypertension) by relaxing blood vessels; it is not a cure. High blood pressure levels can damage your kidneys, and may lead to a stroke or heart failure. Quinapril also helps to treat patients with heart failure (heart does not pump strongly enough). Generic quinapril tablets are available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• autoimmune disease (such as lupus), or suppressed immune function
• previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat (angioedema)
• bone marrow disease
• heart or blood vessel disease
• liver disease
• low blood pressure
• kidney disease
• if you are on a special diet, such as a low-salt diet
• an unusual or allergic reaction to quinapril, other ACE inhibitors, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I take this medicine?

Take quinapril tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. It is best to take quinapril on an empty stomach, at least 1 hour before or 2 hours after meals. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking quinapril except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you take only one dose a day and forget to take it that day, do not take a double dose the next day.

What drug(s) may interact with quinapril?

• antiinflammatory drugs (NSAIDs, such as ibuprofen)
• gold compounds, often used for arthritis
• hawthorn
heparin
lithium
• medicines for diabetes
• medicines for high blood pressure
• monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar™)
• potassium salts
tetracycline
• water pills

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking quinapril?

Visit your prescriber or health care professional for regular checks on your progress. Check your blood pressure regularly while you are taking quinapril. Ask your prescriber or health care professional what your blood pressure should be and when you should contact him or her. Call your prescriber or health care professional if you notice an uneven or fast heart beat. Do not treat yourself for a fever or sore throat; check with your prescriber or health care professional as these may be the result of a quinapril side effect.

Check with your prescriber or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of body fluid can make it dangerous to take quinapril.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how quinapril affects you. To avoid dizzy or fainting spells, do not stand or sit up quickly, especially if you are an older person. Alcohol can make you more dizzy. Avoid alcoholic drinks.

If you are going to have surgery, tell your prescriber or health care professional that you are using quinapril.

Avoid salt substitutes or other foods or substances high in potassium salts.

Do not treat yourself for coughs, colds, or pain while you are using quinapril without asking your prescriber or health care professional for advice.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

What side effects may I notice from taking quinapril?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• decreased amount of urine passed
• difficulty breathing, or difficulty swallowing
• dizziness, lightheadedness or fainting spells
• fast or uneven heart beat, palpitations, or chest pain
• fever or chills
• numbness or tingling in your fingers or toes
• skin rash, itching
• swelling of your face, lips, or tongue

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• change in taste
• cough
• tiredness

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.


An angiotensin-converting enzyme inhibitor used as an adjunct to diuretics for the treatment of heart failure. It is also used to treat all grades of hypertension. It is available as tablets on prescription only.

Side effects, precautions, and interactions with other drugs:
see angiotensin-converting enzyme inhibitors.

Proprietary preparations:
Accupro; Accuretic (combined with hydrochlorothiazide).

See also antihypertensive drugs.

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