| Rachischisis | |
|---|---|
| Classification and external resources | |
| ICD-10 | Q05, Q76.0 |
| ICD-9 | 741, 756.17 |
| MeSH | C10.500.680.800 |
Rachischisis (Greek: "rhachis - ῥάχις" - spine, and "schisis - σχίσις" - split) is a developmental birth defect involving the neural tube. In utero, the neural tube fails to close completely. This anomaly originates when the posterior neuropore fails to close by the 27th intrauterine day. As a consequence the vertebrae overlying the open portion of the spinal cord do not fully form and remain unfused and open, leaving the spinal cord exposed. Patients with rachischisis have motor and sensory deficits, chronic infections, and disturbances in bladder function. This defect often occurs with anencephaly.
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