Raymond Gosling

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Professor Raymond Gosling for 2003 "DNA at King's - the continuing story: 50th anniversary of the discovery of the structure of DNA"

Raymond Gosling (born 1926) is a distinguished scientist who worked with both Maurice Wilkins[1] and Rosalind Franklin at King's College London in deducing the structure of DNA, under the direction of Sir John Randall[2]. His other KCL colleagues included Alex Stokes and Herbert Wilson.

Contents

Early years

He was born in 1926 and attended school in Wembley. He studied physics at University College London from 1944 to 1947 and became a hospital physicist at the King’s Fund and Middlesex Hospital between 1947 and 1949 before joining King's College London as a research student.[3]

Double Helix
Discovery
Dna-split2.png
William Astbury
Oswald Avery
Francis Crick
Erwin Chargaff
Max Delbrück
Jerry Donohue
Rosalind Franklin
Raymond Gosling
Phoebus Levene
Friedrich Miescher
Linus Pauling
Sir John Randall
Erwin Schrödinger
Alex Stokes
James Watson
Maurice Wilkins
Herbert Wilson

Work at King's and DNA

At King's College London, Gosling worked on X-ray diffraction with Maurice Wilkins, analyzing samples of DNA which they prepared by hydrating and drawing out into thin filaments and photographing in a hydrogen atmosphere.

Gosling was then assigned to Rosalind Franklin when she joined King's College London in 1951. Together they produced the first X-ray diffraction photographs of the "form B" paracrystalline arrays of highly hydrated DNA. She was his academic supervisor. During the next two years, the pair worked closely together to perfect the technique of x-ray diffraction photography of DNA and obtained at the time the sharpest diffraction images of DNA. This work led directly to the 1962 Nobel Prize for Physiology or Medicine being awarded to Francis Crick, James D. Watson and Maurice Wilkins. Gosling was the co-author with Franklin of one of the three papers published in "Nature" in April 1953.[4]

Gosling briefly remained at King's College London following the completion of his thesis in 1954 before lecturing in physics at Queen’s College, University of St Andrews, and at the University of the West Indies.[3]

Work at Guy's Hospital

He returned to the UK in 1967 and became Lecturer and Reader at Guy's Hospital Medical School, and Professor and Emeritus Professor in Physics Applied to Medicine from 1984. Here he helped develop the underlying basic medical science and technology for haemodynamic doppler ultrasound vascular assessment in the Non Invasive Angiology Group, and set up the clinical Ultrasonic Angiology Unit.[5][6][7][8]

Gosling has served on numerous committees of the University of London, notably relating to radiological science, and still retains an active professional involvement in medical physics.

See also

References and sources

  1. ^ Wilkins, M.; Gosling, R.; Seeds, W. (1951). "Physical studies of nucleic acid". Nature 167 (4254): 759–760. Bibcode 1951Natur.167..759W. doi:10.1038/167759a0. PMID 14833383.  edit
  2. ^ Gosling, R.; Tickle, C.; Running, S. W.; Tandong, Y.; Dinnyes, A.; Osowole, A. A.; Cule, E. (2011). "Seven ages of the PhD". Nature 472 (7343): 283–286. doi:10.1038/472283a.  edit
  3. ^ a b "King's College biography". http://www.kcl.ac.uk/depsta/iss/archives/dna/faq7.html. Retrieved 2006-11-29. 
  4. ^ Wilkins, Maurice (2003). The third man of the double helix the autobiography of Maurice Wilkins. Cambridge, Eng: University Press. ISBN 0-19-860665-6. 
  5. ^ Side, C. D.; Gosling, R. G. (1971). "Non-surgical Assessment of Cardiac Function". Nature 232 (5309): 335–336. Bibcode 1971Natur.232..335S. doi:10.1038/232335a0. PMID 5094838.  edit
  6. ^ Laogun, A. A.; Gosling, R. G. (1982). "In vivo arterial compliance in man". Clinical Physics and Physiological Measurement 3 (3): 201–212. Bibcode 1982CPPM....3..201L. doi:10.1088/0143-0815/3/3/004. PMID 7140158.  edit
  7. ^ Kontis, S.; Gosling, R. G. (1987). "A computerized method for processing of spectrally analysed Doppler-shifted signals from insonated arteries". Journal of Medical Engineering & Technology 11 (3): 108–112. doi:10.3109/03091908709018151.  edit
  8. ^ Baskett, J. J.; Lewis, R. R.; Beasley, M. G.; Gosling, R. G. (1990). "Changes in Carotid Artery Compliance with Age". Age and Ageing 19 (4): 241–246. doi:10.1093/ageing/19.4.241. PMID 2220482.  edit - Abstract

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