The brother of vocalist Arthur Prysock, Red Prysock is a hard-driving, energetic tenor saxophonist who has not only backed his brother on several hits for Old Town in the '50s and '60s, but also played with Tiny Bradshaw. Red Prysock also was a popular jukebox artist in the mid-'50s for Mercury, though none of these singles got enough general exposure to become national hits. ~ Ron Wynn, All Music Guide
In 1954, he signed with Mercury Records as a bandleader, and had his biggest hit, the R&Binstrumental "Hand Clappin'" in 1955. That same year, he joined the band that played at Alan Freed's stage shows. He also played on several hit records by his brother, the singer Arthur Prysock, in the 1960s.