abbr. : RE; a DNA sequence (sometimes called a 'module') that is common to promoters/enhancers of genes whose expression is coordinately regulated (see
coordinate induction/repression). Examples: the estrogen response element (
ERE) has the consensus sequence GGTCANNNTG[A/T]CC; the glucocorticoid response element (
GRE) has the consensus sequence TGGTACAAATGTTCT; xthe heat-shock response element (
HSE) has the consensus sequence GNNGAANNTCCNNG; the metal response element (
MRE) has the consensus sequence CGNCCCGGNCNC; the serum response element (
SRE) has the consensus sequence CATATTAGG; and the thyroid response element (
TRE), which is common to several enhancers, has the consensus sequence TGACTCA. RE-1 (
or NRSE) is a conserved 21 — 23 bp response element present in neuron-specific genes. See
REST